How to improve the efficiency of hot reflux extraction and concentration unit

How to improve the efficiency of the hot reflux extraction and concentration unit? Many new technologies, processes and materials are used in the hot reflux extraction and concentration process Therefore, compared with the traditional concentration process, the process adaptability of the hot reflux extraction and concentration process system is better, and the recovery rate is higher than that of the traditional process The main reason is that in the process system of thermal reflux, the extraction and concentration of medicinal materials can be carried out at the same time When the hot reflux extraction equipment is selected to extract and concentrate the medicinal materials, the extraction time is relatively short, and the temperature is also lower than the traditional way, which can save the solvent to a certain extent, and the operators are also lower than the traditional way, and the work efficiency is relatively high I overview of the hot reflux extraction and concentration process The process flow of the hot reflux extraction and concentration system is highly automated Its principle mainly refers to the simultaneous operation of the extraction tank and the concentrator of the medicinal materials to achieve the effect of extraction and concentration The work flow is as follows: first, put 5-10 times of the solvent of medicinal materials and medicinal materials in the extraction tank, such as pure water, ethanol, etc (the specific solvent category needs to be determined according to the needs) Open the steam valve of the extraction tank and cook the medicine in the tank for about 1 hour After cooking, open the vacuum and transfer the medicine in the extraction tank to the heater Then, the heating and evaporation process of the heater will be carried out, and some juice steam will be generated in the steam process, and the extraction tank will be heated by the juice steam Then, open the buffer water storage tank for the second steam condensation, and guide the remaining liquid into the spray pipe at the top of the extraction tank After 3-4 hours of circulating operation, close the previously used valves, such as the extraction tank steam valve Then the paste collection work is mainly completed by opening the steam valve of the second heater to heat the steam After the ointment is discharged, put the remaining colorless liquid in the extraction tank into the storage tank to prepare for the next reuse Some slag produced in the process of thermal reflux should be discharged from the slag gate in time If it is necessary to extract the organic solvent, a certain amount of water can be added again, and the solvent can be recovered by opening the straight through and jacket steam, and the remaining drug residue shall be discharged Note that when the hot reflux extraction method is selected, the extraction temperature is generally 40-100 ℃ for water extraction and 50-80 ℃ for ethanol extraction 2 The reason for improving the paste collection rate of the hot reflux extraction and concentration process system The determination of the paste collection rate is very important for the extraction of drugs and new articles, which is directly related to the selection of future dosage forms and the determination of the preparation process If it involves traditional Chinese medicine, its data will also have a certain impact on the future drug delivery program, so it is of great significance In the field of traditional Chinese medicine, paste collection rate is an important production and management index in the pharmaceutical industry of Chinese patent medicine, which is directly related to the quality and cost of products Both manufacturers and manufacturers attach great importance to the paste collection rate of drugs Different from western medicine, which judges the quality of drugs by the content of chemical components in products, the rate of ointment collection is unique to traditional Chinese medicine When the recovery rate of a drug is relatively high, it means that the extraction of this drug is relatively complete, and the ingredients of the drug are relatively pure to a certain extent In the field of tea production, the quality of a kind of tea is directly reflected by the collection rate of a kind of tea 3 The method to improve the recovery rate of the hot reflux extraction and concentration process system The recovery rate is mainly calculated by dividing the amount of cream output by the amount of drug feeding It generally refers to the recovery rate of dry cream During the determination, 25ml of the constant volume solution can be absorbed After the solution is dried, it can be put into the weighing evaporation dish for vacuum drying until it reaches the constant weight state The formula for calculating the paste collection rate is as follows: paste collection rate (%) = (weighed dry paste weight x dilution multiple / medicine weight) X100% The main way to improve the recovery rate is to pay attention to the appropriate amount of solvent in the hot reflux shrinkage extraction process, to improve the extraction time within a certain range, and to increase the extraction times reasonably First of all, in order to improve the recovery rate, we must pay more attention to the selection of materials No matter how to improve the technology, we can not fundamentally improve the recovery rate by concentrating and extracting some medicinal materials with less powder Secondly, in the process of concentration, compared with the traditional three-way or two-way concentration of traditional Chinese medicine, the effect of membrane concentration is more ideal Membrane concentration mainly adopts the combination of ultrafiltration and reverse osmosis Moreover, it needs to use high-speed centrifugal dryer to remove water from the extract In the process of drying the liquid extract into dry extract, attention should be paid to avoid the loss of the liquid extract and unnecessary loss In general, to improve the paste collection rate, it is necessary to control the feeding scale and the particle size of the medicinal materials, the feeding sequence is accurate and correct, and reasonably plan the extraction process parameters (soaking time, heating time, holding time, intermediate mixing or circulation time, etc.) If the paste receiving rate can not be improved all the time, it is necessary to consider the conversion process or reformulate the formula In our country, the extraction and concentration methods of animals, plants and other drugs are not very complete The hot reflux extraction and concentration process system is currently a relatively common method for extraction and concentration In this system, as an important index, the recovery rate is directly related to the results of extraction and concentration Therefore, it is very necessary to improve the recovery rate in the hot reflux extraction and concentration process The basic method to improve the recovery rate is to improve the effect of extraction and concentration, and pay attention to the drying process of flow extract At the same time, in the process of promotion, we also need to pay attention to the principle of appropriate amount, and control the paste receiving rate within a reasonable range.