How to save hair loss?

As we all know, obesity is related to the development of many human diseases

Under normal circumstances, high-fat stem cells will renew themselves during each hair follicle cycle

"A high-fat diet consumes high-fat stem cells, thereby accelerating hair thinning, especially in elderly mice

"Even if fed high-fat foods for four consecutive days, high-fat stem cells showed signs of increased oxidative stress and epidermal differentiation

Senior author Emi K.

The researchers confirmed that in this process, the activation of the Sonic hedgehog signaling pathway can save the depletion of HFSCs

This research provides interesting new insights into specific cell fate changes and tissue dysfunction that may occur after high-fat diet or gene-induced obesity, and may open the door to the future prevention and treatment of thinning hair and understanding of obesity-related diseases

Original search:

"Obesity accelerates hair thinning by stem cell-centric converging mechanisms," was published in Nature at DOI: 10.