HUAMN BRAIN MAPPING: CBF as an alternative method for measuring rs-FC

The intrinsic functional network consists of widely distributed brain regions that are statistically dependent on low-frequency (<0.
1 Hz) activity fluctuations
.

The intrinsic functional structure of the brain can be measured by resting-state functional magnetic resonance imaging (rs-fMRI)

The intrinsic functional network consists of widely distributed brain regions that are statistically dependent on low-frequency (<0.

Resting-state functional connectivity (rs-FC) is widely used to study the functional architecture of the brain, and blood oxygen level-dependent (BOLD) signaling is often used to determine rs-FC

Yuko Nakamura et al.

Since acquisition duration is one of the important parameters for obtaining reliable rs-FC, we investigated the effect of acquisition duration on CBF-based rs-FC to examine the reliability of CBF-based rs-FC
.

Nineteen participants underwent 50-minute cerebral blood flow scans

Since acquisition duration is one of the important parameters for obtaining reliable rs-FC, we investigated the effect of acquisition duration on CBF-based rs-FC to examine the reliability of CBF-based rs-FC

Relationship between acquisition duration and overall functional connectivity estimates (correlation coefficients) (a) and variance (b)

The variance of CBF-based rs-FC at any duration was not different from that of the 50-min duration (p > 0.
05)

In each brain network, obtain the relationship between duration and functional connectivity estimates (correlation coefficients)

In each brain network, obtain the relationship between duration and functional connectivity estimates (correlation coefficients)

The acquisition time required to obtain a reliable CBF-based estimate for the variance of rs-FC in each large-scale brain network is less than 10 minutes, and there are differences among large-scale brain networks
.

The acquisition time required to obtain a reliable CBF-based estimate for the variance of rs-FC in each large-scale brain network is less than 10 minutes, and there are differences among large-scale brain networks
.

The acquisition time required to obtain a reliable CBF-based estimate for the variance of rs-FC in each large-scale brain network is less than 10 minutes, and there are differences among large-scale brain networks

This study examined the acquisition time required to obtain reliable CBF-based rs-FC in the whole brain as well as in various large brain networks, with a total scan length of 50 minutes

Although the variance of CBF-based rs-FC gradually decreased with increasing acquisition duration, the strength and variance of CBF-based rs-FC did not differ significantly at different acquisition durations

Furthermore, the variance of the within-network rs-FC appears to be smaller than that of the population average rs-FC, and an acquisition duration of 10 min is sufficient to obtain reliable within-network rs-FC

In conclusion, acquisition time of at least 10 min is required to obtain reliable CBF-based rs-FC
.
These results suggest that CBF-based resting-state functional magnetic resonance imaging (rs-fMRI) can replace BOLD-based rs-fMRI to obtain reliable rs-FC when the total acquisition time exceeds 10 min
.
CBF-based resting-state functional magnetic resonance imaging (rs-fMRI) can replace BOLD-based rs-fMRI to obtain reliable rs-FC when the total acquisition time exceeds 10 min
.
CBF-based resting-state functional magnetic resonance imaging (rs-fMRI) can replace BOLD-based rs-fMRI to obtain reliable rs-FC when the total acquisition time exceeds 10 min
.

 

original source

original source

The effect of acquisition duration on cerebral blood flow-based resting-state functional connectivity.
Yuko Nakamura.
https://doi.
org/10.
1002/hbm.
25843.

The effect of acquisition duration on cerebral blood flow-based resting-state functional connectivity.
Yuko Nakamura.
https://doi.
org/10.
1002/hbm.
25843.
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