echemi logo
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Immunology News > Hum Vaccin Immunother: Persistence of immune response after 4CMenB vaccination

    Hum Vaccin Immunother: Persistence of immune response after 4CMenB vaccination

    • Last Update: 2020-06-16
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit
    Multi-component meningoccal serogroup B vaccine 4CMenB has been shown to be effective in preventing invasive MenB disease in infants and controlling MenB outbreaksNo additional enhanced dose/timing has been determined
    We reviewed eight studies that evaluated the persistence and enhancement of antibodies after the initial 4CMenB vaccination in infants, children, adolescents and adolescents
    The results showed that between 24 and 36 months after the initial infancy, 76-100% of children maintained the assumed serum-protective hSBA titer of the vaccine antigen, while after the first vaccination of the second time in life, it remained at 84-100%Four and 7.5 years after the beginning of puberty, hSBA levels in the vaccine were higher than in the unvaccinated age groupAntibodies are more persistent to NHBA and NadA than to PorA or fHbpEnhanced vaccination can cause a strong memory cancellation response, proving that 4CMenB can be effective in everyone at different ages
    These data can provide a basis for decision-making to optimize vaccination strategies
    This article is an English version of an article which is originally in the Chinese language on and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to with relevant evidence.