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    Home > Active Ingredient News > Study of Nervous System > Human Brain Mapping: Assessment of Stability and Functional Connectivity of Spontaneous Brain Activity in Resting-State Core Networks Using Ultrahigh-Field 7T Resting-State fMRI

    Human Brain Mapping: Assessment of Stability and Functional Connectivity of Spontaneous Brain Activity in Resting-State Core Networks Using Ultrahigh-Field 7T Resting-State fMRI

    • Last Update: 2022-02-20
    • Source: Internet
    • Author: User
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    In psychiatry, the growing need for accurate and reliable biomarkers has fueled research interest in the hope that identifying quantifiable indicators will improve diagnosis and treatment planning for a range of mental health conditions


    In psychiatry, the growing need for accurate and reliable biomarkers has fueled research interest in the hope that identifying quantifiable indicators will improve diagnosis and treatment planning for a range of mental health conditions


    Since the first UHF MRI scanner was approved for use in humans more than 20 years ago, results from different fields of medicine have shown that there are many clear advantages to using the technology


    Irene Neuner et al.


    Mask descriptions of the three core resting-state networks: the default network (DMN, blue), the central executive network (CEN, red), and the salient network (SN, green) overlaid on the MNI152 template


    Mask descriptions of the three core resting-state networks: the default network (DMN, blue), the central executive network (CEN, red), and the salient network (SN, green) overlaid on the MNI152 template


    Depicts the mean value of each functional magnetic resonance imaging (fMRI) parameter (low frequency fluctuation amplitude [ALFF], fractional ALFF [fALFF], local consistency [ReHo], degree centrality calculated from 16 subjects in two sessions [DC])


    Depicts the mean value of each functional magnetic resonance imaging (fMRI) parameter (low frequency fluctuation amplitude [ALFF], fractional ALFF [fALFF], local consistency [ReHo], degree centrality calculated from 16 subjects in two sessions [DC])


    Average matrix of inter-brain functional connectivity of three core resting-state networks in 16 subjects


    Average matrix of inter-brain functional connectivity of three core resting-state networks in 16 subjects


    The mean value of network correlation stability among the three core resting-state networks was expressed as the mean correlation between DMN/SN, DMN/CEN, and SN/CEN


    The mean value of network correlation stability among the three core resting-state networks was expressed as the mean correlation between DMN/SN, DMN/CEN, and SN/CEN


    Individual space studies found that ALFF, ReHo, and DC had strong stability in all three networks, while fALFF had a moderate level of stability


    This study proves that the reliability of the RS connection is significantly improved under the UHF strength, which is higher than that of the conventional field strength


    The high reliability and reproducibility of the three main RS network properties acquired by UHF-MRI suggest that it can serve as a potentially useful tool for finding disease-related biomarkers


    original source

    Test–retest stability of spontaneous brain activity and functional connectivity in the core resting-state networks assessed with ultrahigh field 7-Tesla resting-state functional magnetic resonance imaging

    Test–retest stability of spontaneous brain activity and functional connectivity in the core resting-state networks assessed with ultrahigh field 7-Tesla resting-state functional magnetic resonance imaging Test–retest stability of spontaneous brain activity and functional connectivity in the core resting-state networks assessed with ultrahigh field 7-Tesla resting-state functional magnetic resonance imagingLeave

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