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Substance use disorder (SUD) is prevalent in SUD (FH+) individuals with a family history (FH) , and this increased risk of SUD is likely to be transmitted through complex genetic and environmental / learning mechanisms .
Substance use disorder (SUD) is prevalent in SUD (FH+) individuals with a family history (FH) , and this increased risk of SUD is likely to be transmitted through complex genetic and environmental / learning mechanisms .
Zhishun Wang et al .
Since the risk of SUD is related to anxiety and impulsivity, they also investigated the correlation between these psychological characteristics and volume /SSS .
Since the risk of SUD is related to anxiety and impulsivity, they also investigated the correlation between these psychological characteristics and volume /SSS .
The study found
- The shape of the right anterior hippocampus was markedly inwardly deformed in FH+ adolescents compared with FH- adolescents , whereas the volume of this structure did not differ between groups .
Results of hippocampal shape analysis in FH+ group and FH- group
Results of hippocampal shape analysis in FH+ group and FH- groupThere were no between-group differences in the shape and volume of other subcortical structures
There were no between-group differences in the shape and volume of other subcortical structuresCorrelation analysis of shape-behavior scores in FH+ group
Correlation analysis of shape-behavior scores in FH+ groupThe research team believes that SSS appears to capture topographical features that traditional volumetric analysis cannot
The research team believes that SSS appears to capture topographical features that traditional volumetric analysis cannot
Zhishun Wang's research proves FH+ Zhishun Wang's research demonstrates that introversion of the adolescent right anterior hippocampus may be associated with an increased risk of SUD due to behavioral dysregulation in FH+ offspring .
original source original sourceWang Z , Rodriguez Moreno DV , Cycowicz YM , et al.
Wang Z , Rodriguez Moreno DV , Cycowicz YM , et al.
Shapes of Subcortical Structures in Adolescents With and Without Familial History of Substance Use Disorder[J].
Social Science Electronic Publishing.
Wang Z , Rodriguez Moreno DV , Cycowicz YM , et al.
Shapes of Subcortical Structures in Adolescents With and Without Familial History of Substance Use Disorder[J].
Social Science Electronic Publishing.
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