Hydroxychloroquine/chloroquine treatment is not beneficial to COVID-19 patients or even increase stake in death

A clinical study of nearly 100,000 COVID-19 patients found that treating them with the antiviral drugs hydroxychloroquine and chloroquine did not benefit, and even increased their likelihood of death in hospitalThe findings, published online May 22, 2020 in the lance Lancet, are titled "Hydroxychloroquine or quine with or withaout a macrolide for treatment of COVID-19: a-national registry analysis"images from Lancet, 2020, doi:10.1016/S0140-6736 (20) 31180-6hydroxychloroquine is commonly used to treat arthritis, but statements from public figures, including U.SPresident Donald Trump, who announced his use this week, have prompted governments to buy the drug in bulkChloroquine is an antimalarial drugBoth drugs can have potentially serious side effects, especially arrhythmiaby looking at the records of 96,000 patients at hundreds of hospitals, researchers at Bligh Women's Hospital, Surgisphere, the University of Utah and the University of Zurich Hospital in Switzerland found that taking both drugs actually increased the risk of deaththey compared the results of treatment from four groups of patients: those treated alone with hydroxychloroquine, those treated alone with chloroquine, those treated with a combination of hydroxychloroquine and antibiotics, and those treated with a combination of chloroquine and antibioticsIn addition, there was a control group of patients who were not given these medicationsat the end of the study, about 9% of patients in the control group diedFor those patients treated with hydroxychloroquine or chloroquine alone, 18% and 16.4% died, respectivelyPatients who were treated with a combination of hydroxchloroquine/chloroquine and antibiotics were more likely to die: 22.8% (chloroquine and antibiotic combination therapy) and 23.8% (hydroxychloroquine and antibiotic combination therapy)the researchers estimate that these drugs put patients at a 45 percent risk of dying from COVID-19 compared to underlying health problems"Treatment with chloroquine or hydroxychloroquine does not benefit PATIENTS WITH COVID-19," said Mandeep Mehra, author of thepaper and executive director of the Center for Advanced Cardiology at Brigham and Women's HospitalInstead, our results suggest that they may be associated with an increased risk of severe heart problems and an increased risk of death "
treatment milestone
despite Trump's enthusiasm for using hydroxychloroquine to treat COVID-19, his government's Food and Drug Administration (FDA) issued a warning Brazil's health minister on Wednesday recommended the use of chloroquine and hydroxychloroquine to treat COVID-19, even in mild cases of COVID-19 The UK has ordered 35 million pounds ($42 million) worth of hydroxychloroquine, although many studies have shown that the drug is ineffective in treating COVID-19 and may even be more dangerous than doing nothing "Some countries have advocated the use of chloroquine and hydroxychloroquine alone or in combination as potential treatments for COVID-19," said Frank Ruschitzka, co-author of the paper and director of the Heart Centre at the University Hospital Zurich We now know from our research that the chances of these drugs improving coVID-19 prognosis are quite low Stephen Griffin, an associate professor at the University of Leeds School of Medicine , who was not involved in the new study, said the new study "could be a landmark study in the treatment of COVID-19." "In terms of indications, these drugs should certainly not be used outside the test environment, which can monitor patient complications in a pilot environment," griffin said Clearly, it is both wrong and irresponsible to support the use of these drugs without clinical supervision (Bio Valley Bioon.com) References: 1.Mandeep R Mehra et al Hydroxyquine or withquine or withchlorochloroa macrolide for treatment of COVID-19: a-national registry analysis Lancet, 2020, doi:10.1016/S0140-6736 (20) 31180-6.
2 Christian Funck-Brentano et al Chloroquine e or hydroxyquine for COVID-19: why might they be hazardous? Lancet, 2020, doi:10.1016/S0140-6736 (20) 31174-0.
3 Hydroxychloroquine show no benefit virus, raises death risk: study
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