Hyperbaric oxygen therapy helps improve efficacy in TBI patients

To contribute, please click on theOutside The Information - Welcome to theRef: Wang F,et alNeurol Sci2016 May; 37(5): 693-701doi: 101007/s10072-015-2460-2Epub 2016 Jan 8.)hyperbaric oxygen therapy (hyperbaric oxygen therapy, HBOT) is commonly used to improve cerebral ischemia, hypoxia and cerebral edema in patients with brain injury (traumatic brain, TBI)However, HBOT's efficacy is not accurate and may also cause complications of ear, sinus and lung damageMedical centers lack uniform standards in grasping the HBOT signFei Wang of the First Affiliated Hospital of Kunming Medical University conducted a systematic retrospective study exploring the effectiveness of TBI patients at HBOT, published in May 2016Neurol Scisearched medical databases such as Medline, Cochrane, EMBASE, and Google Scholar Database, and collected literature on eight clinical randomized controlled studies of patients with HBOT and standard-pressure oxygen therapy TBI patients, including clinical data on 519 patientsThrough meta analysis, the GCS score, GOS score, overall mortality rate and post-traumatic stress disorder (PTSD) were compared between the HBOT group and TBI patients in the normal pressure oxygen treatment groupdata analysis, it was found that the improvement of GCS scores in TBI patients in the HBOT group was significantly better than that of the pernormal oxygen treatment group (MD.3.13, 95% CI 2.34-3.001); Oxygen therapy group (MD s 3.78, 95% CI 1.23-11.63, p-0.020), and helps to reduce the overall mortality rate (OR-0.32, 95% CI 0.18-0.57, p.001) At the same time, there was no significant difference between HBOT and pernormal oxygen therapy on PTSD (MD-1.49, 95% CI -5.79-2.80, p-0.496) , the authors note that HBOT can further improve GCS and GOS scores in TBI patients and reduce mortality compared to pernormal oxygen therapy Therefore, it is recommended that HBOT be included in the standardized treatment options for TBI patients (
Ding Chenxuan, of the First Hospital affiliated with Fujian Medical University, compiled , editor-in-chief of "Outside The God Information" and Professor Chen Rongcheng, a subsidiary of Fudan University) review