echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Study of Nervous System > Hypertension: Be alert!

    Hypertension: Be alert!

    • Last Update: 2021-09-29
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Orthostatic hypotension ( OH ) is a common symptom in the elderly, which reflects changes in hemodynamics and body position


    Orthostatic hypotension ( OH ) is a common symptom in the elderly, which reflects changes in hemodynamics and body position


    However, the clinical manifestations of patients with OH are quite different.


    pixabay

    pixabay

    The clinical manifestations of OH are related to hypoperfusion of various organs.


    The clinical manifestations of OH are related to hypoperfusion of various organs.


    Recently, a study published in the journal Hypertension Hypertension showed that OH is associated with an increased risk of dementia, even in the absence of OH symptoms .


    In this study, the researchers used data from the Swedish National Kungshomen Aging and Care Study (SNAC-K) , which regularly followed up approximately 2500 subjects (age ≥ 60 years)


    In this study, the researchers used data from the Swedish National Kungshomen Aging and Care Study (SNAC-K) , which regularly followed up approximately 2500 subjects (age ≥ 60 years)


    It was found that during the 12- year follow-up period, 322 ( 12.


    The relationship between orthostatic hypotension (OH) and the incidence of dementia

    Further analysis of OH-related symptoms showed that compared with asymptomatic OH , symptomatic OH has a stronger correlation with dementia; however, after adjusting for all confounding factors, the association with symptomatic OH is no longer significant


    Further analysis of OH-related symptoms showed that, compared with asymptomatic asymptomatic OH , symptomatic OH is more correlated with dementia; however, after adjusting for all confounding factors, the correlation with symptomatic OH is no longer significant


    Sensitivity analysis showed that when a more stringent definition was used to define OH , there was a stronger correlation between OH and dementia, AD and CIND progressing to dementia, and AD OH and dementia, AD and CIND progressing to dementia and AD .


    The relationship between asymptomatic and symptomatic orthostatic hypotension (OH) and cognitive function

    The relationship between asymptomatic and symptomatic orthostatic hypotension (OH) and cognitive function

    In addition, when OH is classified according to the possible causes , the results show that both non-neurogenous and neurogenic OH are significantly associated with an increased risk of dementia, while only non-neurogenic OH is significantly associated with CIND progression to dementia and AD .


    In addition, when OH is classified according to the possible causes , the results show that both non-neurogenous and neurogenic OH are significantly associated with an increased risk of dementia, while only non-neurogenic OH is significantly associated with CIND progression to dementia and AD .


    In short, the elderly should actively evaluate their postural blood pressure, which is especially important, because orthostatic hypotension is usually asymptomatic.


    Original source

    Xin Xia et al, From Normal Cognition to Cognitive Impairment and Dementia: Impact of Orthostatic Hypotension ,  Hypertension  (2021).


    Xin Xia et al, From Normal Cognition to Cognitive Impairment and Dementia: Impact of Orthostatic Hypotension ,  From Normal Cognition to Cognitive Impairment and Dementia: Impact of Orthostatic Hypotension Hypertension Hypertension  (2021).
      DOI: 10.
    1161/HYPERTENSIONAHA.
    121.
    17454 DOI: 10.
    1161/HYPERSION .
    121.
    17454

    Leave a message here
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Related Articles

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.