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The role of orthostatic hypotension (OH) in the process of cognitive aging remains to be elucidated
.
Recently, the heart blood vessels authoritative magazine published a research article on Hypertension, the researchers tried to investigate OH with Alzheimer's disease, cognitive impairment, no dementia (CIND) and CIND association between progression to dementia
.
This population-based cohort study included 2532 baseline (2001-2004) dementia-free participants (age ≥ 60 years; 62.
6% were women) who were regularly evaluated
.
The researchers further divided the participants into a baseline CIND-free cohort and a CIND cohort
diagnosis
Incidence of dementia
Of the 2532 participants, 615 were defined as OH at baseline, and 322 were diagnosed with dementia throughout the follow-up period
.
The adjusted hazard ratio of OH to dementia was 1.
The results of this study indicate that OH, even asymptomatic OH, is associated with increased risk of Alzheimer’s disease and accelerated progression from CIND to dementia
OH, even asymptomatic OH, is associated with increased risk of Alzheimer’s disease and accelerated progression from CIND to dementia
Original source:
Original source:Xin Xia.
