IBD: Passive smoking increases the risk of intestinal surgery in patients with Crohn's disease

Although the cause of Crohn's disease is unclear and is thought to be the result of a multi-factor effect, studies have shown that nearly 50 percent of adult Crohn's patients have a history of smoking, suggesting that smokers are more likely to develop Crohn's disease.
despite strong evidence of the negative effects of active smoking, the impact of passive smoking on the course of Crohn's disease (CD) remains unclear.
, the purpose of this study was to assess whether passive smoking was a risk factor for CD intestinal surgery.
study included 563 patients with CD.
patients were interviewed for retrospective analysis of passive and active smoking.
retrospective collection of clinical data was conducted.
84 per cent for all respondents to the questionnaire.
to assess the impact of exposure to passive smoking on the risk of intestinal surgery, only patients who had never smoked were included.
result, a statistical analysis was performed on all patients.
91 (54%) of the 169 patients who had never actively smoked were exposed to passive smoking.
exposed patients were more likely to undergo intestinal surgery (67% vs 30% ;P .lt;0.001) than those who were not exposed.
multivariable Cox regression analysis showed that passive smoking was an independent risk factor for intestinal disease after intestinal surgery diagnosis (risk ratio, 1.7; 95% CI, 1.04-2.9; P - 0.034) is also a risk factor for stronger disease behavior or a higher proportion of penetrating behavior (risk ratio, 1.9; 95% CI, 1.2 - 3.1; P - 0.01).
study also found that passive smoking in childhood was a risk factor for becoming an active smoker in later life (OR:2.2; 95% CI: 1.5-3.2; P -lt;0.001).
increases the risk of intestinal surgery in CD patients, the authors of the study concluded.
tells us that active or passive smoking increases the risk of Crohn's disease.