IBD: Secondhand smoke increases the risk of intestinal surgery in patients with Crohn's disease.

!---- The impact of passive smoking on the course of Crohn's disease (CD) is still unclear, despite overwhelming evidence of the negative effects of active smokingthe purpose ofstudy was to assess whether passive smoking was a risk factor for CD intestinal surgeryThemethod study was a case-control study of 563 CD patientsconducted structured interviews with patients who received passive and active smokinga chart check of clinical dataThe response rate ofwas 84 per cent, with 471 cases to be analysedto assess the main objective, namely, the impact of exposure to passive smoking on the risk of intestinal surgery, only included patients who had never smoked activelyresults In 169 patients who did not smoke actively, 91 (54%) were exposed to passive smokingPatients exposedare more likely to undergo intestinal surgery than those who are not exposed (67% vs 30% ;P .lt;001)multivariate Cox regression analysis showed that passive smoking was an independent risk factor for intestinal disease adjustment after intestinal surgery diagnosis (risk ratio, 1.7; 95% CI, 1.04-2.9; P - 0.034) and strengthening or penetrating behavior at diagnosis (risk ratio, 1.9; 95% CI, 1.2-3.1; Ppassive smoking in childhood is a risk factor for active smokers in later life (advantage ratio 2.2; 95% CI 1.5-3.2; P-lt;0.001)conclusion spassive smoking increases the risk of intestinal surgery in CD patients.