IBD: The degree of disease activity of inflammatory bowel disease is related to the occurrence of arterial vascular disease.

!---- background and goals: There is evidence that inflammatory diseases are associated with increased cardiovascular riskstudy aims to assess this risk and validate the effects of conventional vascular risk factors and IBD disease activitymethod: Researchers conducted a cohort study of qualified patients from the UK clinical practice study data chainthey took clinical records of subjects with IBD from 1997 to 2017 and matched the control group, and conducted a series of analyses of Cox proportional risk and self-controlled cases to examine the relationship between IBD, disease activity and hospitalization and the risk of myocardial infarction, stroke and myocardial infarctionand try to eliminate cardiovascular deaths that may cause confusionResults: This study identified a total of 31,175 cases of IBD patients (16779 cases of UC, 10721 cases of Crohn's disease and 3675 cases of unclassified IBD) and 154,412 matching control groups523 cases of myocardial infarction, 555 strokes and 469 cardiovascular deaths were observed in IBD casesCox regression model, adjusted for potential confounding factors, showed that, overall, there was no significant excess of vascular events in PATIENTs with IBD, however, patients with non-beds are at increased risk to acute diseases (risk ratio, 1.83 (1.28-2.62)) and chronic activity (risk ratio, 1.69 (1.24-2.30))Conclusion: Although this study found no evidence of excessive overall vascular events in patients with IBD, the researchers found that active diseases increase disputing cardiovascular disease, and that anti-inflammatory treatment may reduce cardiovascular risk in the patient group.