IBD: There was no increased risk of colorectal tumors in patients with inflammatory bowel disease and inflammatory e. coli.

Both say the risk of colorectal cancer (CRC) increases in patients with inflammatory bowel disease (IBD), while the presence of inflammatory pyrophageal (PIP) due to inflammation also increases the risk of CRC, with the overall prevalence of PIP estimated at 20 to 40 percent in IBD patients.
PIP is a residue of inflammation formed by the substation and cortide components, as well as inflammatory cells, which are associated with long-term IBD inflammation.
case-control studies over the past few decades have shown a 1.9-2.5-fold increase in CRC risk in PIP patients, however, recent large retrospective queue studies have found no increased tumor risk in PIP patients.
in this study, the researchers aimed to assess whether patients with IBD companion PIP had an increased risk of colorectal cancer.
researchers analyzed the cumulative incidence of colorectal cancer in patients with or without PIP and corrected the mixing factors.
154 of the 519 IBD patients in the queue with a mid-level follow-up time of more than 22 years had PIP at the same time.
PIP is associated with a wide range of lesions (OR) of 2.76; 95% of the PIP is 1.61-4.42; P-lt;0.001) and inflammation is more severe during colonoscopy (OR is 3.54; 95% of CI is 2.28-5.50; P .lt;0.001).
the correction of the mixing factors, the presence of PIPs was independent of the development of colorectal tumors (1.28; 95% CI was 0.85-1.93; P was 0.24).
risk of colonectomy in patients with PIP (HR, 3.41; 95% CI, 1.55-7.54; P s 0.002).
, the researchers concluded that PIPPs were associated with higher rates of disease, inflammation and colonectomy.
, the presence of PIPs is independent of tumor development.
findings suggest that PIP patients may not need to strengthen their monitoring strategies.
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