Ic-msms polar anionic agricultural residue solution

On November 5, 2019, semefei officially released a complete solution for the combination of ion chromatography and mass spectrometry at the Rafa conference in Prague, Czech Republic, which is dedicated to the analysis of polar anionic agricultural residues in food The detection of agricultural residues has always been an important project of food safety, which is related to people's livelihood, and also the focus of the public at home and abroad With the continuous development and improvement of GC, GCMs, LC and LCMS methods, a small number of pesticides are still in the difficulties of analysis and cannot be perfected For example, the polar anionic pesticides represented by glyphosate, glyphosate, dipropylaminophosphine, aluminum ethylphosphate, ethephon, etc have the characteristics of small molecular weight, strong water solubility and large polarity The conventional reversed-phase chromatographic column needs derivatization reaction to be retained The HILIC chromatographic column needs a long equilibrium time and poor repeatability In addition, in the EU risk assessment, it is strongly recommended that the sum of agricultural residues and their metabolites be used as the definition of pesticide residues For example, Glyphosate Residues contain the sum of four compounds: glyphosate, AMPA, n-acyl-ampa and n-acyl-glyphosate Therefore, the limit of Zui large residue requires higher sensitivity of agricultural residue analysis to meet the requirements of lower content determination Polar anionic IC pesticide residues ic-ms / MS solution emerges at the historic moment In response to the special needs of polar ionic pesticide residues analysis, thermo fly combines the characteristics of ion chromatography that can directly inject samples to analyze polar and ionic compounds, which has the advantages of flow path without metal materials, and combines with high sensitivity and high selectivity mass spectrometer detector, On November 5, 2019, a complete solution for the combination of ion chromatography and mass spectrometry was officially released at the Rafa conference in Prague, Czech Republic It is specially used for the analysis of polar anionic agricultural residues in food, fully meeting the needs of polar ionic agricultural residues analysis A new solution of polar pesticide residues and pollutants in food analysis - ic-ms / MS system with high sensitivity, high efficiency and high tolerance, one needle injection, simultaneous analysis of 15 compounds The solution can meet the requirements of one injection and simultaneous analysis of 15 compounds, including polar anionic agricultural residues and their metabolites, as well as common anionic pollutants (glyphosate, AMPA, n-acyl-ampa, n-acyl-glyphosate, gluposite, n-acyl-gluposite, MPPA, ethephon, fosetyl Al, phonic acid, cyclic acid, bialophos, chloride, perchlorate, HEPA) this solution includes sample pre-processing process, instrument configuration, consumables supply, software method preset and professional technical support Schematic diagram of integrated ic-ms / MS system: system configuration: ion chromatography Dionex integrity HPIC mass spectrometry TSQ Altis As-ap Dionex autosampler auxiliary pump Dionex axp-ms auxiliary pump and AXP auxiliary pump software Advantages of tracefinder or chromeleon instrument configuration scheme (I) highlights of ic-ms / MS Combined System 1 Anion exchange column, highly efficient separation of substances to be measured, no derivation, cost saving, simplified analysis process 2 Full flow PEEK material, acid and alkali resistant and organic solvent resistant, does not interfere with the test results 3 Online preparation of EGC eluent can provide stable and accurate isocratic and gradient eluent functions Only adding water can automatically generate eluent online, which is convenient for use and reduces pump head maintenance 4 The on-line electrolytic suppressor provides continuous and stable inhibition function, making the ion chromatography system compatible with mass spectrometry 5 Altis mass spectrometer has the characteristics of high sensitivity and high selectivity 6 The combined system can provide triple protection to ensure that the mass spectrometry system is not polluted (II) method validation is consistent with EU regulations 1 Optimization of pre-treatment method this set of solution will provide customers with optimized pre-treatment method Refer to the quppe extraction method of EU laboratory, optimize the extraction process and purification process for different types of samples, and simefei can provide all consumables related to pre-treatment At present, the related pretreatment methods include grain, fruit, vegetable and infant food In the future, we will continue to develop pretreatment methods for different samples 2 Methodology validation the methodology validation of the solution is in accordance with the provisions of Sante 11813 / 2017, including linearity inspection, standard addition level and repeatability test All the results are consistent with the provisions, and meet the requirements of recovery rate of 70% - 120%, and repeatability RSDS of less than 20% Scheme Application (1) sensitive flour is generally considered to be a kind of sample with complex matrix The figure below is the peak figure of Zui low point (equivalent to 4 ng / g sample content) of standard curve in flour matrix The sensitivity of 15 compounds can meet the requirements of EU (II) recovery and repeatability: take flour as an example for 10NG / g spiked recovery results The results of four flour samples are shown in the figure below, which meet the requirements of EU Sante 11813 / 2017 with recovery of 70% - 120% and RSDS less than 20% (III) system stability and tolerance take glyphosate in onion matrix as an example Statistics of ion pair proportion and retention time of 124 injections: comparison of peak shape before and after 500 injections of continuous injections containing matrix samples: ic-ms / MS combined solution helps customers break through more technical problems Samefei is with you in the way of scientific research Scan the QR code below to get the whole industry solution of Symantec, or pay attention to the public Hao of "Symantec chromatography and mass spectrometry China", for more information +