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With the Winter Olympics looming, many will soon be tuning in for ice competitions such as figure skating, speed skating and ice hockey
.
The ultra-thin, ultra-lubricating layer of water on the ice is critical to a skater's graceful glide
Osteoarthritis is a chronic disease common in the middle-aged and elderly population, characterized by persistent inflammation and degeneration of articular cartilage
.
Anti-inflammatory drugs can help relieve pain and inflammation, but long-term use can reduce their effectiveness or cause gastrointestinal problems
The researchers based their particles on hyaluronic acid (HA), a natural polysaccharide already used as a lubricant for osteoarthritis, but the molecule degrades quickly in the body
.
So the researchers used a microfluidic device to create tiny methacrylic anhydride-HA gel particles, which they believe may be stronger than HA solutions and stay in the body longer
The authors thank the National Key R&D Program, the National Natural Science Foundation of China, the Natural Science Foundation of Jiangsu Province, and the Shenzhen Basic Research Program for funding
Magazine
ACS Nano
DOI
10.
