IEEE trans: Study on effective brain connectivity of Ld-EEG in patients with tidal breathing

Heart failure (heart failure) referred to heart failure, the heart is due to the yield contraction function and (or) diastolic function disorder occurs can not be sufficiently discharged cardiac venous return blood, resulting in deposition of blood venous system, arterial system hypoperfusion, whereby Causes cardiac circulatory disorder syndrome, which is manifested in clusters of pulmonary congestion and vena cava congestion .

It is manifested as tide (tide) Cheyne-Stokes breathing (CSR) .
CSR is a type of periodic breathing (PB), which is characterized by alternating hyperventilation, with a typical increasing-decreasing pattern and central apnea , with a duration of up to 60 seconds

Heart failure (heart failure) referred to heart failure, the heart is due to the yield contraction function and (or) diastolic function disorder occurs can not be sufficiently discharged cardiac venous return blood, resulting in deposition of blood venous system, arterial system hypoperfusion, whereby Causes cardiac circulatory disorder syndrome, which is manifested in systolic and/or diastolic dysfunction, which can not fully discharge the venous return to the heart, leading to blood stasis in the venous system and insufficient blood perfusion in the arterial system, thereby causing cardiac circulation Disorder syndrome, which is manifested in clusters of pulmonary congestion and vena cava congestion

Patient's EEG signal

The severity of CSR is assessed by multi-map, and physiological parameters including airflow, respiration, and oxygen saturation signals are obtained.
From this, apnea-hypopnea index (AHI), central apnea index (CAI), and oxygen saturation index ( OAI) and the time when the oxygen saturation is below 90% (T90)
.

In addition, electroencephalography (EEG) has been widely used to assess sleep fragmentation and arousal tendency, which is related to apnea during sleep

This article analyzes the EEG clinical records of patients with HF and CSR to assess the impact of CO ₂ changes caused by the CSR cycle at the cortical level , and evaluates the classic EEG frequency bands of cortex-cortical interactions during CSR in patients with systolic heart failure (ie, δ, θ, α, β, low γ) significant difference in RPDC value

Clustering results of all subjects who showed CSR during the experiment

Outpatients diagnosed with systolic heart failure and CSR were included in the study
.

The patient was asked to close his eyes and relax during the experiment while lying on the bed, staying awake, with the light on

Sixteen outpatients affected by systolic heart failure (all male, age 74±9 years old, left ventricular ejection fraction 25.
0±7.
5%) and CSR participated in this study
.

However, during the EEG recording process, only 8 subjects showed consistent CSR patterns

The method proposed in this article can be applied to future clinical research.
From a physiological point of view, this research opens a new perspective for further research on brain connectivity in the control of the respiratory center
.

The method proposed in this article can be applied to future clinical research.
From a physiological point of view, this research opens a new perspective for further research on brain connectivity in the control of the respiratory center
.

AL Callaraet al .

AL Callaraet al .

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