Improve the solubility of red pepper carotenoids

researchers found that mixing red pepper carotenoids with sugar compounds increased the solubility of carotenoids, making them available as natural pigments or bioactive substances.Researchers at the Federal University of Flominence in Brazil have studied how to improve the solubility of the two main types of carotene
-
capsaicin and capsaicin in bell peppers, enabling them to be used as a natural food and beverage pigment or as a functional ingredient.they cite research published in the
2012-
Journal of Molecules and
's 2010-
Visual Research:A balanced diet rich in carotenoids is associated with the prevention of diseases such as tissue cancer and macular degeneration.
”They added:
"
however, the low water solubility of carotenoids and their instability in light, heat treatment and oxidation hinder their use in food and pharmaceutical formulations.
”Extended Applicationsresearchers have previously found that bell pepper carotenoids in
β-
cyclodext can be efficiently mixed with yogurt, but are less desirable when applied to liquid beverages. "
"
led us to look for alternatives that not only protected the molecules, but also made it possible to compound applications in water-based foods," they wrote.
”They speculated that water solubility would be better when carotenoids were combined with
2-
hydroxypropyl
-β-
cyclodextycin (
2-HP-beta-CD
), a water-soluble modified cyclodext. According to the researchers, the U.S. Food and Drug Administration (
FDA
) classifys natural cyclodext (including
β-
cyclodext) as generally recognized as safe (
GRAS
), while the European Union's reference guidelines say the daily allowable intake of
β-
cyclodext as a food additive (
ADI
) is
5mg/kg/kg/
.added:
"
The purpose of this survey was to use ultrasound emulsification to prepare a
package of different mixing ratios of
2-HP-beta-CD

(1:4, 1:6, 1:8
and
1:10).
”The researchersred peppers purchased from the Rio de Janeiro market, placed them in an industrial mixer, and used a mixture of ethanol and distilled water solvents to extract pigments.is saponified, washed, and carotenoid dissolved in
HPLC
-grade acetone. The extract is then dispersed in ethanol, and hydroxypropyl cyclodext is dissolved in
45
ml of ethanol and water mixture solvent. The two extracts are mixed in four different proportions using ultrasonic probes.Observations researchers found that the sample had a minimum water solubility of
8.00mg/ml
and a maximum of
16.55mg/ml
after the red pepper pigment molecules were packed, indicating an increase in the solubility of the extract
320-660
times, so they concluded that this could be used as a way to increase the solubility of carotene. researchers said:
"
in our team's previous work has found it very difficult to add red pepper pigment and
β-
cyclodextin compounds to water-borne media. Samples are easy to precipitate, limiting their use in a variety of foods, especially beverages.
” They added: "
"
's data on the solubility of carotenoids obtained in this study expanded its reach in a wide variety of foods, such as desserts, teas, juices, soft drinks, jelly, candy, ice lollies, soluble powders, and other foods.
” The source of this
is
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