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There are more than 1.4 million survivors of colorectal cancer (CRC) in the United States.
previous studies have shown that dietary quality has a significant impact on disease prognosis, and that some pre- and post-diagnosis dietary components are associated with the survival rate of CRC patients.
studies to assess overall dietary quality and CRC-specific mortality were inconsistent, making it difficult to develop evidence-based recommendations for CRC survivors. For more information, the researchers, led by Dr. Mark A. Guinter, a postdoctoral researcher at the American Cancer Society, reviewed data on 2,801 men and women diagnosed with CRC in the American Cancer Society's Large Prospective Cancer Prevention Study-II (CPS-II) nutrition team.
they found that those who dieted before and after diagnosis that met the American Cancer Society's guidelines on nutritional and physical activity to prevent cancer had lower overall and CRC-specific mortality rates.
the pre-diagnosis diet group, which was most consistent with the ACS diet recommendations, had a 22% reduction in total mortality and a significant reverse trend in CRC-specific mortality compared to the control group.
after diagnosis of dietary patterns are also significantly associated with risk of death.
patients with the highest ACS scores had a 65 percent reduction in CRC mortality and a 38 percent reduction in all causes compared to those with the lowest ACS scores.
, therefore, they concluded that dietary quality could be a potential way to improve the prognosis of CRC patients.
so far, there has been no separate study to assess the relationship between pre- and post-diagnosis dietary quality changes and mortality risk in CRC survivors, the first of its studies.
Dr. Mark A. Guinter said.
overall, the results prove that high dietary quality after diagnosis, even if previously poor, may be associated with a lower risk of death.
this undoubtedly gives clinicians another mission to help patients change their lifestyle habits that are incompatible with their healthy lifestyles, after standardizing and rationaltreatment programs, with a view to improving the prognosis for colorectal cancer to the greatest extent.
Source: Biological Exploration.