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    Home > Biochemistry News > Natural Products News > In addition to making women young and beautiful, collagen can also repair Durant's torn Achilles tendon!

    In addition to making women young and beautiful, collagen can also repair Durant's torn Achilles tendon!

    • Last Update: 2019-09-09
    • Source: Internet
    • Author: User
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    September 9, 2019 news / BIOON / - tendon injury can happen in an instant With a loud bang and severe pain, even the most ordinary athletes' life style may be changed forever Jeff ruberti, a professor of bioengineering at Northeastern University in the United States, has experienced the unfortunate lesson: at a meeting in 2017, when he was playing temporary football, in order to change direction, his foot was stepped on, and his Achilles tendon broke immediately "You can't do anything for the time being," ruberti recalled I started watching 100 of the greatest movies from the beginning to the end, with my feet up and my toes down, waiting for it to heal Almost two months later, I used a plastic boot, and I haven't fully recovered "At present, there are only a few tendon repair options available, and they do not always allow patients to fully recover their previous activity," he said Surgeons usually either let the tendon heal itself or sew together the loose ends of the tear Both treatments require intense physical therapy before the patient begins to recover Photo source: https://cn.bing.com ruberti may have found a better way He studies collagen, the connective tissue that connects most of our bodies, and he thinks manipulating collagen can speed up the recovery time of tendon injury "Collagen is a structural molecule of invertebrates In every tissue, it takes different forms, from tendons to corneas It's made up of tiny molecular chains that are assembled into larger and larger chains that hold our cells in place "These molecules have special properties When you put them in a dish, they don't form anything - but ruberti found that if you start pulling them, they start to bite into each other, forming recognizable, linear structures "It's a fundamental discovery," he said "Our research shows that when collagen is stretched, it will assemble itself into a natural load-bearing structure This means that when you pull it, it's more stable than when you don't "He concluded that if it is possible to place collagen molecules in the wound and apply the appropriate load, the damaged tendon may heal faster than the existing method However, it is not easy to do so Injecting loose collagen into tendons doesn't do much, because most of it floats away from the wound before the tendons self assemble In order to be truly successful, these molecules must stay directly on the damaged tissue, and the surrounding muscles will contract and pull this area, causing the collagen molecules to connect Photo source: https://cn.bing.com to accomplish this feat, ruberti's lab processes collagen into two different forms The first is a gelatinous substance called "metastable collagen", which provides loose collagen molecules for injured tendons The other is a stable and dense collagen pad that can wrap the tendons and fix the gel in situ "Think of a broken Achilles tendon as a broken rope," he said "The stable collagen is like a piece of tape, wrapped in the damaged place, connecting the two ends together But in the tape, we put high density collagen molecular gel, which can help the tendon repair If we stimulate the calf muscles to contract slightly, the tendons may start to absorb these molecules "In this process, collagen may accumulate in the growth chain, where the cells that produce the living tendon - tendon cells - can stabilize and grow "It's a completely different way of thinking about tendon repair," he added Ruberti has begun to consider bringing the technology to market He started a small company with former Northeastern University doctoral student Patrick Bradley and former orthopaedic researcher Adam hacking, hoping to eventually turn the lab's work into a viable treatment He has tested some aspects of the technology in the laboratory and is now doing animal experiments If successful, he thinks the new collagen technology may be priceless for professional athletes and elite soldiers, who rely on keeping their bodies at their best to do their jobs Photo source: https://cn.bing.com he said: "professional football teams spend millions of dollars training their top players The same thing happened with seal commandos and army training, which cost millions of dollars But people who work in both jobs can be hurt by training and lose their jobs altogether "He said Using this new method, not only can the damaged tendons be repaired faster, but also can let them return to the high-intensity work and reduce the fear of repeated injury Ruberti added that it can not only improve the lives of good athletes, but also the lives of faltering professors If he is lucky, he will be able to free the rest of us from the eight week sofa Reference: [1] can collapse help fix impaired tendens? These tissue engineers think so 【2】 Recently identified molecule could lead to new way to repair tendons
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