|Indigenous bacteria let fish eat sugar and grow meat|
Zebrafish Photo courtesy of Feed Institute of Chinese Academy of Agricultural SciencesZebrafish Photo courtesy of Feed Institute of Chinese Academy of Agricultural Sciences
You may not know that fish can hardly grow meat while eating sugar.
Recently, the aquatic animal feed innovation team of the Feed Research Institute of the Chinese Academy of Agricultural Sciences discovered that Cetacea Sorbii can improve the sugar utilization ability of fish and play an important role in regulating the health of fish.
According to Zhou Zhigang, the corresponding author of the paper and the chief researcher of the team, fish generally have low sugar utilization capabilities.
It has been known that the animal intestinal flora plays an important role in regulating the host's sugar metabolism, but the mechanism by which the fish intestinal flora plays a regulatory function has been seldom studied before and is not yet clear.
According to Ran Chao, the co-corresponding author of the paper, they found that the difference in zebrafish's sugar utilization ability caused by different feeds is mediated by the intestinal flora, and it is extremely positively correlated with the abundance of Cetacea sorghum in the intestine.
Further research found that Cetaceae Soxhlete promotes the expression of insulin in zebrafish and lowers blood sugar.
Ran Chao introduced that both cetacea and acetic acid can activate the expression of insulin through the regulation of the parasympathetic nervous system and promote the sugar utilization ability of fish.
This result proves for the first time in the world that the cetacea sockii in the intestinal flora plays an important role in the health of fish, and clarifies that cetyl sockii activates the parasympathetic nervous system through its metabolite acetic acid, thereby promoting insulin expression and sugar utilization.
Zhou Zhigang said that Cetaceae Soxhlete and its regulation of sugar metabolism provide new ideas for improving the sugar utilization capacity of fish, which can promote the development of functional feed supplements based on Cetaceae and related prebiotics.
The research was funded by the National Natural Science Foundation of China's Outstanding Youth Fund Project and the National Key Research and Development Program "Blue Granary".
Related paper information: org/10.