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    Home > Biochemistry News > Biotechnology News > Industrial marijuana offers new hope for fighting brain cancer

    Industrial marijuana offers new hope for fighting brain cancer

    • Last Update: 2020-06-06
    • Source: Internet
    • Author: User
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    Long-term incurable diseases that harm human beings - brain cancergliomas, the color change, brain tumor fatal disability rate is the second highest of all tumorsStatistics from the Shanghai CDC show that compared with the 1980s, the incidence of brain tumors in men increased by 1.2 times and that of women by 2.2 times, posing a serious threat to human lifeEven celebrities and politicians, such as Taiwanese writer Li Wei and Vice President Joe Biden's eldest son, Beau Biden, can do little about brain cancerAt present, in the world, with the progress of various technologies, once called cancer king, cancer after liver cancer, lung cancer, five-year survival rate is rapidly increasing, on the contrary, there has been no breakthrough in medicine for 30 yearsin the past 30 years, the incidence of primary malignant brain tumors has been increasing year by year, with an annual growth rate of about 1.2%, especially among the elderlyAccording to statistics, the annual incidence rate of glioma in China is 6.2 per 100,000 people, far higher than the world averageShanghai area every year about 1200-1500 new cases of glioma, China's annual death toll due to glioma is tens of thousandsBrain tumor fatality and disability rate is the second highest of all tumors, a serious threat to human lifeLi Wenbin, deputy director of the professional committee of theChina Anti-Cancer Association and director of the Neurosurgery Neurotumor Integrated Treatment District of Beijing Tiantan Hospital, said, "Compared with other malignant tumors, brain tumors are neglected, but in fact, brain tumors represented by glioma are one of the most difficult cancer strains to overcome in China's cancer battle." As the most common malignant brain tumor, the incidence rate is about 45% of intracranial tumors"
    Mawang Pharmaceuticals (Shenzhen) Co., Ltdand Zhongshan University School of Medicine Drug Molecular Design Research Center after years of joint research, launched anti-glioblastoma drug research, recently, finally obtained exciting research results - successful synthesis of a number of cannabis CBD coupling, with high efficiency through the blood-brain barrier of the former drug compound, and broke through the anti-glioma drugs and other technical barriers, this research will be the international pharmaceutical industry's achievementscannabinoid CBD brings new hope to fight brain cancer to break the blood-brain barrier problem
    glioma (commonly known as brain cancer), is still defined by medicine as incurable disease The blood-brain barrier gives the human brain tissue unlimited protection, maintains the relative stability of the central nervous system, and protects the brain from injury But when the brain "gets sick", it becomes a burden: brain tumors, Parkinson's, Alzheimer's disease, schizophrenia, and so on, many of the drugs that are effective against them, are ruthlessly shut out by the blood-brain barrier Because of this, "how to penetrate the blood-brain barrier" has become the focus of the fight against brain cancer after years of research, designed and synthesized the parent compound and cannabinoid CBD conjugate compound "CGBM1" (substitute) anti-glioma drug, which acts as a rocket, penetrates the human blood-brain barrier directly to the brain lesions, killing cancer cells completely study found that cannabinoid CBD could be used as a "Trojan horse": carrying drug molecules into the blood-brain barrier to achieve therapeutic results In this study, cannabinoid CBD was the main force behind the "break through the blood-brain barrier." blood-brain barrier consists of a densely connected cell that prevents some substances in the blood from entering the brain Cannabinoids, on the other hand, go directly through the blood-brain barrier into the brain to function the current research of animal experiments has been completed in stages, has accepted applications for domestic and international patents, the next step will enter the human experiment stage As an important ingredient in new anti-brain cancer drugs, cannabinoid CBD will not only shock the global medical community, but also hopefully make a big step forward in the fight against brain cancer will soon set up the first special research laboratory for industrial cannabis in 2020, Mawang Group and Zhongshan University School of Medicine, will soon set up China's first special research laboratory for cannabinoids - "Shenzhen Industrial Cannabis Application Research Collaborative Innovation Laboratory", focusing on the bioactive ingredients in industrial cannabis, in-depth study of CBD cannabinoids, and the establishment of anti-infection, anti-tumor, anti-aging virtual screening platform and industrial natural cannabis chemical structure database.
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