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Because in influenza and other respiratory virus infections , bacterial superinfection can lead to higher morbidity and mortality, prompt diagnosis and antibiotic treatment (ABT) are required
.
The use of antibiotics reported in the 2019 Coronavirus Disease ( COVID-19 ) is much higher than the actual ratio of bacterial co-infection and superinfection.
Because in influenza and other respiratory virus infections , bacterial superinfection can lead to higher morbidity and mortality, prompt diagnosis and antibiotic treatment (ABT) are required
Researchers included 6,457 SARS-CoV-2 infection cases in the LEOSS cohort between March 18, 2020 and February 16, 2021
.
For adult patients with procalcitonin (PCT) ≤ 0.
Finally, a total of 3627 patients met the inclusion criteria for the analysis
.
For the primary observation endpoint, the researchers found that antibiotic treatment was not associated with lower all-cause mortality or progression to the next more serious disease stage (n=996) (p>0.
This study confirms that SARS-CoV-2 infection patients receiving antibiotic treatment will not improve all-cause mortality or disease progression
.
.
Original source:
Maximilian J.
All-cause mortality and disease progression in SARS-CoV-2-infected patients with or without antibiotic therapy: an analysis of the LEOSS cohort.
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