echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Medical News > Latest Medical News > Inject once a week! Noel and NORD long-acting insulin are declared clinical in China.

    Inject once a week! Noel and NORD long-acting insulin are declared clinical in China.

    • Last Update: 2020-10-12
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    A Phase II clinical trial showed that icodec insulin is used in adult type 2 diabetics in blood sugar control and safety characteristics similar to the daily injection of insulin glycerion U100.
    The 26-week study included 247 adult type 2 diabetics who had not previously used insulin, who had not previously used metformin, who had not used metformin or who did not use DEP-4i, and were designed to compare the efficacy and safety differences between icodec insulin injected once a week and insulin glyceride U100 injected daily.
    end point is the HbA1c change from baseline to 26 weeks.
    end points include changes in peri-abdominal blood sugar from baseline to 26 weeks and the number of hypoglycemia events.
    results showed that participants who received weekly injections of icodec insulin from baseline to 26 weeks had similar changes in blood sugar control (HbA1c) to participants who received daily insulin insulin glycemic U100 treatment (-1.33% vs-1.15%, p-0.08, respectively) to reach the primary endpoint.
    secondary endpoints included changes in peri-abdominal blood sugar from baseline to 26 weeks, similar changes in the icodec insulin group and insulin glycemic U100 (-58mg/dL and -54mg/dL, respectively); p - 0.01).
    safety, the rates of hypoglycemia were similar in the two treatment groups, and no new safety issues associated with icodec insulin were found.
    icodec insulin is a long-acting underlying insulin similar in study with a half-life of 196 hours.
    icodec insulin binds tightly but reversiblely to albumin when injected into the body.
    results can reduce blood sugar continuously, slowly and steadily over a period of one week.
    based on its concentrated formula, the amount of icodec insulin injected once a week is comparable to the amount of insulin Glycelin U100 injected daily.
    .
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Related Articles

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.