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    Home > Active Ingredient News > Infection > Int J Antimicrobial Agents: Early use of antibiotics in non-severe COVID-19 patients with sterile infections cannot achieve effective treatment

    Int J Antimicrobial Agents: Early use of antibiotics in non-severe COVID-19 patients with sterile infections cannot achieve effective treatment

    • Last Update: 2021-11-12
    • Source: Internet
    • Author: User
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    The new crown pandemic has brought major challenges to the current global health system, but so far there is still no specific drug for the new crown virus ( COVID-19 )
    .


    Although it is not recommended to treat patients with viral infections with antibiotics , antibiotics are common in certain countries, especially in the early stages of COVID-19 patients


    The new crown pandemic has brought major challenges to the current global health system, but so far there is still no specific drug for the new crown virus ( COVID-19 )


     

    This study is a multi-center retrospective cohort study that included a total of 1,373 non-severe COVID-19 hospitalized patients who were admitted to the hospital without bacterial infection
    .


    According to the patient's exposure to antibiotics within 48 hours after admission, the patients were divided into two groups, the antibiotic treatment group and the non-antibiotic treatment group


     

    During the 30-day follow-up, the proportion of patients in the early antibiotic use group who progressed to severe COVID-19 was almost 1.
    4 times that of the control group
    .


    In the mixed-effects model, early use of antibiotics is associated with a higher likelihood of developing severe illness and hospitalization for more than 15 days


     

    This study found that the early use of antibiotics in non-severe COVID-19 patients is significantly related to the risk of progression from non-severe to severe and the length of hospital stay
    .


    The researchers also found that the use of azithromycin was not associated with better clinical outcomes


    This study found that the early use of antibiotics in non-severe COVID-19 patients is significantly related to the risk of progression from non-severe to severe and the length of hospital stay


     

     

    Original source:

    XiaoxvYin.


    Evaluation of early antibiotic use in non-severe COVID-19 patients without bacterial infection: Early antibiotic use in non-severe COVID-19.
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