Introduction to primary biliary cirrhosis and its quality of life scale (PBC-40)

Primary biliary cirrhosis ( Primary biliary cirrhosis in, the PBC) is performed intrahepatic bile duct disease of unknown cause destruction and chronic cholestatic as the main feature.

Pathogenesis

Primary biliary cirrhosis undergoes four typical stages of development.

Symptoms and signs

Although primary biliary cirrhosis can occur in men and women of all age groups, more than 90% of them occur in female patients between 35 and 70 years old, and they are often latent.

Laboratory examination

The early laboratory examination results of the disease showed the characteristics of cholestasis, and it was accompanied by disproportionate increase in alkaline phosphatase and γ-glutamyl transaminase and serum bilirubin and transaminase.

Videography

Ultrasound, ERCP, CT, PTC, etc.

Evaluation

PBC-40 score of health-related quality of life indicators for patients with primary biliary cirrhosis (PBC), see: medsci.

The diseases to be differentially diagnosed include: extrahepatic biliary obstruction, chronic active hepatitis, primary sclerosing cholangitis, and drug-induced cholestasis.

The development process of primary biliary cirrhosis is different, which may not affect the quality of life of patients for several years.

treatment

No specific treatment.

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