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    Home > Biochemistry News > Biotechnology News > Introduction to the similarities and differences between totipotent nucleases and DNases

    Introduction to the similarities and differences between totipotent nucleases and DNases

    • Last Update: 2022-08-30
    • Source: Internet
    • Author: User
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    Abstract of this issue: Nucleic acid degradation is very important in molecular biology technology



    Totipotent nuclease is an endonuclease from Serratia marcescens




    DNase is a nucleic acid hydrolase that can only cut double-stranded DNA



    The optimum pH of DNase I is between 7.


    deoxyribonuclease


    The optimum pH of DNase II is between 4.


    Induces multiple single-strand breaks within the DNA backbone


    Key applications of DNase II include the preparation of DNA-free RNA and protein extracts, and the removal of template DNA during in vitro transcription



    Both are hydrolases



    Nucleases are widely used in different experiments in molecular biology and genetic engineering


    The Pannarase all-purpose nuclease & ELISA detection kit is used for virus purification processes such as vaccines, cell and gene therapy
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    No animal origin, no amikacin , strict endotoxicity control
    Excellent unit specific enzyme activity, more efficient nucleic acid degradation ability Accuracy of activity and stability between batches Advanced production process, non-traditional His tag purification, eliminates the risk of introducing metal ions, there is a matching nuclease ELISA detection kit, direct antibody coating with high sensitivity and wide linear range (0.
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