Introduction to water maze and introduction of equipment parameter setting and experimental process

The water labyrinth is indeed an extremely challenging job of endurance and physical strength

What is a water maze?

The water maze experiment is an experiment that uses the water-weary nature of animals to force animals to look for hidden platforms in the water

Water maze application areas

Water Maze is currently the most used behavioral experimental method in Alzheimer's disease research, which is widely used in learning memory, Alzheimer's disease, hippocampus and other related research, involving intelligence and aging, cognitive drug development/screening/evaluation, pharmacology, toxicology, preventive medicine and other neurological diseases and neuroscience-related research fields, and is the most recognized classic experiment

How to set the equipment parameters of the water maze?

However, like many animal behavior experiments, the experiment in different papers has great differences in terms of equipment specifications, experimental procedures and data statistics, which are often confusing, and it is not clear whether there is a unified standard for the water maze experiment, which parameters can be changed, and which parameters need to be carefully considered

Before introducing the experimental process, we need to understand the two major elements of the water maze experiment, the driving force and the assessment content

B: Under normal circumstances, the visual platform experiment lasts for 2 days, the hidden platform period is 4-6 days, and the last day is removed from the platform for the detection of mouse spatial memory;

C: After completing the experiment in B in some cases, the researchers will repeat the hidden platform period and space exploration experiment again to the placement of the platform position, testing the mouse's ability to