Introduction, use and source of NBS.
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Last Update: 2020-10-30
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Source: Internet
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Author: User
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related topics . NBS brominated
reagents
and brominated reactions NBS
3D molecular modelIntroduction 1. N-bromosuccinimide, N-Bromide amberamide (chemical name) N-brominated diamide (N-bromide) osuccinimide
NBS
also known as N-Bromide Amberamide, 1-Bromine-2, 5-Pyridoxine) is a very useful brominated agent, it is highly selective, only attack weak C-H bonds that attack the double-bond or benzene ring connected to the alpha;-H. The first reactant in the last reaction in the structural diagram.used
in
NBS to brominate and has been shown to be done through a constant, very low concentration of bromine. This bromine is obtained by reaction-generated HBr and NBS, where traces of HBr or Br2 are commonly found. The reaction journey is as shown.the Chinese name of the bromide aminide; N-Bromide amberamide;
NBS .Structure or
Molecule
)Relative Molecular Weight or Atomic Mass: 177.99Density: 2.098Melting Point (C) 173 to 175 (slightly decomposed)Toxic LD50 (mg/kg)has strong irritation, irritation, irritation, skin and mucous membranes.theis the white orthomorphic crystalline crystallization of theorthomorphic system, with a slight bromine odor.:Solubility (g/100g): slightly soluble in water (1.47 at 25 degrees C), statins (0.73 at 25 degrees C), positive hexane (0.0 at 25 degrees C) 006), carbon tetrachloride (0.02 at 25 degrees C), benzene, chlorine, soluble in acetone (14.40 at 25 degrees C), acetic acid (3.10 at 25 degrees C) and ethyl acetate.-use used as a select brominated agent for the synthesis of streptic olefins and
organic
;is a very useful brominated agent, it is highly selective, only attack the weak C-H key, that is, attack with the double bond or benzene ring connected to the alpha;-H.preparation or sourcereacts with ammonia with butyric acid to produce ammonium butyric acid, dehydrates at 250 degrees C, and produces butylamin, after
filtration
then the diamide powder in the cooling and stirring to add to sodium hydroxide, so that it dissolves, then add a mixture of bromine and carbon tetrachloride solution, reaction, after the reaction, with ice cooling, crystallization, filtration, washing with ice water and ethanol, low temperature
drying
and get.
.
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