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Scientists at the University of Exeter in the UK have developed a new method that allows users to measure the pH of individual bacteria before, during and after antibiotic treatment
This study, published in the journal mBio, laid the foundation for understanding the special characteristics of bacteria that survive antibiotic treatment, so that new methods can be developed for them
The research team at the University of Exeter found that even before antibiotic treatment, the intracellular pH of common infections that cause E.
Antibiotic resistance is one of the most pressing public health challenges, threatening the ability to effectively fight infectious diseases
A research team at the University of Exeter discovered a mechanism that allows persistent bacteria to have an acidic pH
Dr.
The team is currently working to expand this research to find out whether cell acidity plays a key role in the antibiotic resistance of other key bacterial pathogens such as Pseudomonas aeruginosa and Bokholderia pseudo-Omar, and Identify drug molecules that can change the pH of persistent cells before antibiotic treatment
Journal Reference :
Olivia Goode, Ashley Smith, Ashraf Zarkan, Jehangir Cama, Brandon M.