Is female trauma survival rate, life expectancy higher than men's because of estrogen?

It is well known that the overall survival rate of women is higher than that of men, and that women usually live longer than men for several years.
this survival advantage is particularly easy to observe in animal models of trauma and sepsis - but the principles that explain this advantage have long been unknown.
scientists have previously concluded that estrogen should be a determining factor. A recent report was considered authoritative because it lasted 11 years and involved more than 800,000 patients. What
determine? Under normal circumstances, women's life expectancy is already longer than men's, and a 2018 study by a team of Danish and German teams showed that women live longer than men even in harsh environments: in several harsh crises in the history of the study, women live longer than men by six months to four years.
, although the competitors are only "male" and "female" two, but "female" is always the life champion? Previously, scientists have determined that both physiological and behavioral factors play an important role, and physiological causes are likely to be directly related to estrogen.
in this light, in the latest study, a Swedish team explicitly wants to explore whether estrogen determines a woman's survival advantage.
team focused on the physical advantages of severe trauma, and they looked at data on 815,843 people admitted to hospital between 2001 and 2011 for falls, traffic accidents or attacks, from Sweden's national patient database and the cause of death database.
54% of all respondents were women.
their findings, women's hormones, especially estrogen, do not seem to explain the higher survival rates of women after severe trauma than men.
it wasn't about estrogen? The researchers studied people hospitalized for three fatal traumas - falls, traffic accidents and assaults - and found that women had an overall survival advantage over men.
but when women were divided into three age groups - ages 0 to 14, ages 15 to 50 and over 50 (premenstrual, post-fertility and menopause) - they found no significant difference between the three groups. Robert Larson, a scientist at The University of Linchepin in Sweden, who
the study, explains: "We used to believe that survival advantage is due to estrogen, but if hormones are so important, there must be a greater survival advantage in the life phase of hormone-producing."
What we have observed is that if there is a certain pattern, it is also a pattern that women's survival advantage may improve somewhat with age.
this further proves that the difference in survival between men and women is due to other principles, not estrogen levels.
" and women's survival advantages did not differ between age groups, and the age groups with typically higher estrogen levels (15 to 50 years) did not show greater advantages and the mortality rate was not significantly lower than in other age groups.
the findings therefore fail to validate what previously thought was "the protective nature of estrogen and a major factor in women's survival advantage after trauma."
the cause of gender superiority in serious injuries Robert Larson says that in the general perception, women's survival rates are generally better than men's, and women live longer than men, a condition that scientists have previously tested in trauma animal models but has been unable to explain its rationale.
people expect to clearly and accurately clarify this mechanism, thus uncovering the secret of the high survival rate of women, while helping the medical community to improve the nursing prognosis of trauma.
but the researchers caution that because the age group used in this study to represent hormone levels, there may be a mismatch between classification and actuality.
another notable study that also appeared recently, and a paper published in the Scandinavian Journal of Trauma, Recovery and Emergency Medicine found that men were more likely than women to enter the intensive care unit in 6,865 trauma patients attended by emergency care at three trauma centers in the Netherlands between January 2006 and December 2014.
researchers also found that female patients between the ages of 16 and 44 had a survival advantage.
however, this gender advantage among seriously injured patients has been studied for many years, and the physiological mechanism remains unknown.
(Science and Technology Daily, Beijing, March 26) Source: Science and Technology Daily