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    Home > Medical News > Latest Medical News > Is plasma therapy effective? They gave a scientific answer

    Is plasma therapy effective? They gave a scientific answer

    • Last Update: 2020-11-26
    • Source: Internet
    • Author: User
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    may still have fresh memories of Wuhan centenarians' victory over the new coronary pneumonia. At the time, doctors used recovery plasma therapy, and the old man became the oldest patient to be cured by the treatment.
    the plasma therapy during the recovery period have any definite effect on the treatment of patients with neo-coronary pneumonia? This question needs a scientific answer.
    Recently, the Journal of the American Medical Association, an international medical academic journal, published the latest study by one of the co-authors, Associate Professor Zhang Wei of the Respiratory Critical Medicine Department of the First Affiliated Hospital of naval military medical university, "The Therapeutic Effect of Recovery Plasma on Severe and Critical New Coronary Pneumonia". This is the world's first recovery plasma treatment of neo-coronary pneumonia multi-center randomized control study.
    back to February 24, a centenarian who had been diagnosed with neo-crown pneumonia was transferred to Guanggu Hospital District of The Hubei Provincial Maternal and Child Health Hospital, where Zhang Wei supported the fight against the disease. After a period of treatment, the elderly's condition was under control, but the new coronavirus test is always positive. In a room inspection, Zhang Wei and Professor Zeng Li, director of infection department of Guanggu Hospital District, put forward a plan for recovery plasma therapy, which will cure the recovered patients rich in antibody blood after a series of treatment and then infusion to the elderly, the expert group after discussion adopted this treatment plan.
    72 hours, the virus test for the elderly turned negative. After many tests were negative, the elderly were successfully discharged from the hospital.
    recovery plasma therapy is a traditional blood transfusion treatment, which plays a role in the treatment of new outbreaks of infectious diseases such as Severe Acute Respiratory Syndrome (SARS), Ebola haemorrhagic fever and Middle East Respiratory Syndrome. However, due to the lack of high-quality randomized controlled clinical trials, its efficacy has not been determined.
    can we use scientific methods to prove that recovery plasma can effectively treat patients with neo-coronary pneumonia? This successful treatment, opened Up Zhang Wei's scientific research ideas.
    coincidence, in order to explore treatment options for patients with neo-coronary pneumonia, the Liu Zhong team of the China Institute of Medicine
    Blood Transfusion is also conducting a randomized controlled study of the efficacy of recovery plasma therapy in patients with neo-coronary pneumonia.
    learned this information, Zhang Wei took the initiative to get in touch with them. With his efforts, Guanggu Hospital District of Hubei Maternal and Child Health Hospital became the clinical research sub-center of the project.
    wuhan anti-epidemic period, Zhang Wei's infection of a cumulative number of 107 cases of new crown pneumonia patients, including 9 heavy, 7 critical, and successfully applied ECMO to rescue 1 person. 18 cases of elderly patients over 70 years of age, 10 cases over 80 years of age, 3 cases over 90 years of age, the oldest 100 years of age. All the staff are working under heavy load, and Zhang Wei ran up to 8 sick areas a day, consultation patients 22 cases!
    but tired again to adhere to high-quality completion of the subject research, because "ultimately overcome the epidemic, the key depends on science and technology."
    " tired, I am not afraid, the military belongs to the battlefield, Guanggu courtyard area is my battlefield. Zhang Wei said that he must be able to afford this uniform.
    not responsible for kung fu, in this study, Hubei Province Maternal and Child Health Hospital Guanggu Hospital District admitted to the group of patients ranked first in the single center.
    final study found that when the combination of severe and critical cases was carried out for population-wide analysis, the main observational indicators after plasma therapy in the recovery period of the trial group -- the difference between clinical improvement time and control group -- were not statistically significant. The strated analysis found that the clinical improvement rate was 91.3% in severe patients, better than 68.2% in the control group, and there were significant differences in clinical improvement time, with 13 days in the trial group and 18.5 days in the control group. In critically ill patients, the clinical improvement rate of the trial group was close to that of the control group. In the secondary observation index, there was no statistical difference in the 28-day death rate of the whole population compared with the control group, and the 72-hour nucleic acid transition rate in the experimental group was 87.2%, significantly higher than the 3
    % in the control group.
    reporters learned that although compared with the control group, the trial group patients 28 days of clinical improvement rate or mortality is not statistically significant improvement, but did provide an important hint of possible benefits in the severe patient subgroup, and showed that anti-neocyclovirus (SARS-CoV-2) high-titration antibodies may be effective. The research results provide an important basis for the treatment of new coronary pneumonia.After the
    paper was published, Liu Zhong of the China Institute of Medicine
    Blood Transfusion Evaluation said: As an important participating unit in this research, Guanggu Hospital District of Hubei Maternal and Child Health Hospital has played an important role, reflecting the high level of scientific research strength and rigorous work style of
    Hospital.
    A review published in the Journal of the American Medical Association at the same time noted that this is an important achievement and a clinical study of precise control of new highly contagious diseases during an epidemic pandemic under unprecedented pressure on human health.
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