Is the mouse safe under a strong magnetic field? Scientists give answers

The Center for Strong Magnetic Field Science of the Chinese Academy of Sciences announced today (June 5) that the research team of Zhang Xin, a researcher at the center, has made new progress in the biosecurity of 20 Tesla-class strong magnetic fields using a large scientific device of steady-state strong magnetic fields, and has reported for the first time the effects of strong magnetic fields above 20 Teslas on the main physiological and biochemical indicators of normal mice. The results were published online in the international journal Neuroimaging.
team members conducted a small-scale experiment in the early stages, testing the effect of 3.7 to 24.5 Tesla strong magnetic field on the mouse with a 9-hour treatment time, and found that it could have a certain inhibitory effect on tumor growth. Although most physiological and bio-chemical indicators in mice were not significantly abnormal, their livers were affected by a strong magnetic field.
On the basis of the previous experiments, the team reduced the strength of the magnetic field, shortened the processing time of the magnetic field, treated 112 normal mice for 2 hours under the strength of 3.5 to 23 Tesla field, and then continued to breed normally for three weeks, comprehensively and systematically testing their biological safety.
Through pathological sliping, routine blood testing and blood biochemical analysis, the researchers found that this treatment did not cause significant harm to the mice's main organs (heart, liver, spleen, lungs, kidneys), blood routine indicators and liver and kidney function, lipid metabolism and ion concentration and other major physiological indicators. Although the feeding and weight gain of the 23 Tesla treatment group mice were affected, the strong magnetic field of 21.9 Tesla and below was not significantly affected.
" is of positive significance in defining the biosecurity boundary of strong magnetic field and developing the application of strong magnetic field in medical and instrumentation fields. Zhang Xin said.
it is understood that with the development of technology, in order to improve tissue resolution and imaging function, the steady-state magnetic field strength applied to MRI scanners in hospitals has generally increased from the initial 0.5 Tesla to 1.5 Tesla or 3 Tesla. However, due to the relative shortage of strong magnetic field equipment above 10 Teslas, research on the biosecurity of strong magnetic fields in steady states is currently lacking, while research on the safety of strong magnetic fields above 20 Teslas is closer to blank. Therefore, it is of great scientific and practical significance to explore the biosecurity of steady-state strong magnetic field for the development and clinical application of higher field MRI scanners.
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