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Japanese Prime Minister Shinzo Abe recently announced his decision to resign as prime minister after a recurrence of ulcerative colitis.
Abe suffered from ulcerative colitis at the age of 17 and has not been cured for nearly 50 years.
is ulcerative colitis an "incurable disease"? Professor Wang Lingyun, Department of Digestive Medicine, Sun Yat-sen Memorial Hospital, Zhongshan University, said that although ulcerative colitis is a chronic disease with a long course of illness, it is not a flood beast, as long as strict follow-up to the guidance of a specialist, regular medication, regular follow-up, most patients have a good prognosis.
ulcerative colitis is difficult to diagnose and is often confused with these diseases ulcerative colitis (UC), an unexamined chronic inflammatory disease of the intestine, which is presumed to be related to environmental, genetic, intestinal micro-ecological and immune imbalances.
Patients often have persistent or recurrent episodes of diarrhea, abdominal pain and mucus pus, some patients can appear severe anemia, low albuminemia, wasting, fever and other systemic symptoms, in addition to external arthritis, oral recurrent mouth ulcers and other extraintestinal manifestations.
Professor Wang Lingyun said that the diagnosis of ulcerative colitis has no gold standard, often requires a full body and local comprehensive hematological examination, imaging examination (CT/MR), endoscopy (gastroscopy, colonoscopy, capsule endoscopy), pathology examination, microbiological examination, etc., by combining recurrent or persistent diarrhea, abdominal pain, mucus Symptoms such as pus, typical endoscopic performance and pathology, such as comprehensive judgment, excluding infectious enteritis, Crohn's disease, isohemic bowel disease, radioactive enteritis, colorectal cancer and other diseases can appear similar clinical manifestations can be diagnosed, and sometimes even after a comprehensive and detailed examination still can not be diagnosed, need to go through a long period of follow-up observation to be able to diagnose.
do not pay attention to healthy diet, may lead to ulcerative colitis ulcerative colitis in Europe, North America and other Western developed countries, before the incidence of low incidence in China, belongs to a relatively rare disease.
with the changes in diet, living habits and environment, the incidence of ulcerative colitis in Asia and even China has increased year by year, and has become a common disease in digestive diseases.
epidemiological data in China show that the incidence of ulcerative colitis also varies greatly from region to region, and its incidence is positively related to the level of economic development in the region.
Wang Lingyun, China's existing data show that the peak age of the disease is 20 to 49 years old, can also be seen in children or the elderly, gender differences are not obvious.
in Western countries, studies have suggested that excessive intake of animal proteins, lyic acid, sugar, fat and alcohol increases the risk and recurrence of ulcerative colitis.
Reduced dietary fiber intake, increased intake of processed foods and saturated fatty acids are thought to be associated with ulcerative colitis, whereas increased vegetable, fruit and high-fiber diets can reduce the risk and progression of ulcerative colitis.
, temperature changes, negative emotions (depression, negativity) may also be associated with the recurrence of ulcerative colitis.
low-intensity aerobic exercise can improve the intestinal inflammatory response of patients during the remission period and reduce recurrence.
patients with ulcerative colitis often experience malnutrition, which is not conducive to the relief of the disease, and the occurrence of ulcerative colitis is closely related to diet, therefore, patients should attach great importance to the daily diet.
recommends eating a low-fat, high-dietary fiber, high-vitamin, moderate-quality protein diet to avoid supplements such as sea products, dairy products, ginseng and deer antlers, as well as irritating, indigestible foods.
more than 20 years, the risk of colon cancer increased 10-15 times! Professor Wang Lingyun said that ulcerative colitis is a chronic disease, most patients have repeated seizures, need long-term medication to maintain the condition, inappropriate diet, infection, bad mood, etc. may lead to the recurrence or exacerbation of the disease, mild and long-term remission of the prognostic better.
the preferred medical treatment for ulcerative colitis, surgical treatment is required for patients with ineffective medical treatment or serious complications such as haemorrhage, perforation of the intestines, toxic large colons, or cancer.
after the control of acute conditions, the physician will adjust the plan according to the specific situation of the patient to maintain remission, maintenance of treatment according to the patient's specific condition, generally not less than 4 years.
From the range of lesions, the risk of cancer of extensive colon ulcerative colitis is highest, followed by the left half colon type;
Data show that patients with a course of more than 20 years have a 10-15 times increased risk of colon cancer than normal people, so it is recommended that patients with extensive colitis and left semi-colonitis with a course of more than 15 years have a monitored colonoscopy every 2 years.
In addition, ulcerative colitis combined with primary sclerotic bileitis patients significantly increased the risk of cancer, and cancer time significantly earlier, for this group of people should pay more attention to colon cancer screening.
have ulcerative colitis, can you have children? The reasons behind Mr Abe and his wife's failure to have children are unknown.
and the good age of ulcerative colitis overlaps with the peak fertility period, many patients face the contradiction between treatment and fertility.
because the disease activity period increases the rate of infertility, increases the risk of adverse pregnancies, and reduces drug safety, it is not recommended that patients choose to have children when the disease is active.
but there was no significant difference between the reproductive capacity of patients during the remission period and the normal population, and they could choose to have children under the guidance of a specialist.
Wang Lingyun reminded that MTX (methotrexate), salidamine has a clear teratogenic effect, family planning should be avoided, recommended to stop the drug 3-6 months after pregnancy.
more research on infrifflixi monoantigen (IFX) in biological preparations, and it is generally considered safe for women to use during pregnancy.
In the case of unwanted pregnancies, it is not recommended to deactivation of the drug on its own because of concerns about the side effects of the drug, and the adverse events of pregnancy caused by active periods or exacerbation of the disease are far greater than those caused by the majority of the drug itself, so it is recommended that the drug should be developed under the guidance of a specialist.
source: 39 Health.com!-- content presentation ends -- !-- determine if the login ends.