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Yimaitong conference report, please do not reprint without authorization
.
Introduction: As the positive effects of continuous blood glucose monitoring system (CGM) are gradually recognized by doctors and patients, the application of CGM is becoming more and more common
.
Most scholars believe that CGM is of great significance to the monitoring and control of blood glucose in diabetic patients
.
This study from Japan shows that the CGM system has a positive effect on improving the quality of life of diabetic patients
.
CGM and traditional blood glucose monitoring means intermittent scanning continuous blood glucose monitoring system (isCGM) and real-time dynamic continuous blood glucose monitoring system (rtCGM) belong to the category of continuous blood glucose monitoring system (CGM).
The difference is that isCGM is passed multiple times (10 times and The above) measures blood glucose instead of real-time dynamic continuous monitoring to reflect the user's blood glucose trend.
However, compared with the traditional self-blood glucose monitoring (SMBG) method, the data obtained is still more representative and comprehensive
.
At the EASD (European Society for Research on Diabetes) 2021 annual meeting held on September 28, a research team from the Kyoto Medical Center of the National Hospital of Japan conducted a cross-over study, ISCHIA, which aims to compare isCGM and self-glucose monitoring ( SMBG) for improving the quality of life of people with type 1 diabetes
.
Kei Murata Japan National Hospital Kyoto Medical Center Diabetes Center ISCHIA study The ISCHIA study is a randomized crossover study of patients with type 1 diabetes who receive multiple injections a day
.
The study included 104 eligible participants with an average age of 51.
4±15.
3 years, 52.
7% of the participants were women, an average HbA1c of 7.
3±0.
7%, and 46.
2% of the participants had never used isCGM
.
The study used isCGM monitoring as the intervention group and SMBG monitoring as the control group
.
The whole process includes a 28-day run-in period, 84-day sequence 1, 28-day clearance period, and 84-day sequence 2
.
In Sequence 1 and Sequence 2, the researchers were randomly assigned to the intervention group and the control group
.
As Japan's relevant regulations on the CGM system require isCGM and SMBG to be used in combination, all participants will use traditional methods to monitor blood glucose more than 3 times a day during the entire study period, but the participants themselves cannot see the measurement results
.
The primary endpoint of the trial is the decrease in the time to hypoglycemia (<70mg/dL) per day
.
Research results: isCGM combined with structured education significantly reduced the duration of hypoglycemia 1.
Blood glucose levels and fluctuations ➤ Compared with the control group (3.
10±2.
28 hours/day), the intervention group (2.
42±1.
68 hours/day) had daily hypoglycemia Time was significantly reduced (P=0.
012); ➤There was no significant difference in the time (TIR[70-180mg/dl]) of glucose within the target range between the two groups (14.
54±2.
66 hours/day vs.
13.
75±2.
45 hours/day) ); the time of glucose exceeding the target range (>180mg/dl) was 7.
03±3.
12 hours/day and 7.
15±3.
50 hours/day, respectively
.
2.
Glycated protein (GA) level ➤ There was no significant difference in the change of glycated protein (GA) between the two groups (0.
3±2.
3% vs.
0.
1±2.
3%); 3.
Adverse events ➤ The frequency of severe hypoglycemia (SH) was between two groups.
There was no significant difference between the groups (2.
1% vs.
6.
5%); ➤Except for severe hypoglycemia, no serious adverse events related to the study occurred; there was no significant difference in the frequency of non-serious adverse events related to the study between the two groups (17.
0% and 17.
4%, respectively)
.
Research conclusions The researchers believe that the use of isCGM combined with structured education significantly reduces the duration of hypoglycemia in type 1 diabetic patients, improves the quality of life of diabetic patients, and does not adversely affect key diabetes indicators such as TIR and GA
.
Yimaitong Endocrine Group Scan the QR code to join the "Yimaitong-Endocrine Group", you can enjoy the benefits of lecture review, Q&A and free guides~
.
Introduction: As the positive effects of continuous blood glucose monitoring system (CGM) are gradually recognized by doctors and patients, the application of CGM is becoming more and more common
.
Most scholars believe that CGM is of great significance to the monitoring and control of blood glucose in diabetic patients
.
This study from Japan shows that the CGM system has a positive effect on improving the quality of life of diabetic patients
.
CGM and traditional blood glucose monitoring means intermittent scanning continuous blood glucose monitoring system (isCGM) and real-time dynamic continuous blood glucose monitoring system (rtCGM) belong to the category of continuous blood glucose monitoring system (CGM).
The difference is that isCGM is passed multiple times (10 times and The above) measures blood glucose instead of real-time dynamic continuous monitoring to reflect the user's blood glucose trend.
However, compared with the traditional self-blood glucose monitoring (SMBG) method, the data obtained is still more representative and comprehensive
.
At the EASD (European Society for Research on Diabetes) 2021 annual meeting held on September 28, a research team from the Kyoto Medical Center of the National Hospital of Japan conducted a cross-over study, ISCHIA, which aims to compare isCGM and self-glucose monitoring ( SMBG) for improving the quality of life of people with type 1 diabetes
.
Kei Murata Japan National Hospital Kyoto Medical Center Diabetes Center ISCHIA study The ISCHIA study is a randomized crossover study of patients with type 1 diabetes who receive multiple injections a day
.
The study included 104 eligible participants with an average age of 51.
4±15.
3 years, 52.
7% of the participants were women, an average HbA1c of 7.
3±0.
7%, and 46.
2% of the participants had never used isCGM
.
The study used isCGM monitoring as the intervention group and SMBG monitoring as the control group
.
The whole process includes a 28-day run-in period, 84-day sequence 1, 28-day clearance period, and 84-day sequence 2
.
In Sequence 1 and Sequence 2, the researchers were randomly assigned to the intervention group and the control group
.
As Japan's relevant regulations on the CGM system require isCGM and SMBG to be used in combination, all participants will use traditional methods to monitor blood glucose more than 3 times a day during the entire study period, but the participants themselves cannot see the measurement results
.
The primary endpoint of the trial is the decrease in the time to hypoglycemia (<70mg/dL) per day
.
Research results: isCGM combined with structured education significantly reduced the duration of hypoglycemia 1.
Blood glucose levels and fluctuations ➤ Compared with the control group (3.
10±2.
28 hours/day), the intervention group (2.
42±1.
68 hours/day) had daily hypoglycemia Time was significantly reduced (P=0.
012); ➤There was no significant difference in the time (TIR[70-180mg/dl]) of glucose within the target range between the two groups (14.
54±2.
66 hours/day vs.
13.
75±2.
45 hours/day) ); the time of glucose exceeding the target range (>180mg/dl) was 7.
03±3.
12 hours/day and 7.
15±3.
50 hours/day, respectively
.
2.
Glycated protein (GA) level ➤ There was no significant difference in the change of glycated protein (GA) between the two groups (0.
3±2.
3% vs.
0.
1±2.
3%); 3.
Adverse events ➤ The frequency of severe hypoglycemia (SH) was between two groups.
There was no significant difference between the groups (2.
1% vs.
6.
5%); ➤Except for severe hypoglycemia, no serious adverse events related to the study occurred; there was no significant difference in the frequency of non-serious adverse events related to the study between the two groups (17.
0% and 17.
4%, respectively)
.
Research conclusions The researchers believe that the use of isCGM combined with structured education significantly reduces the duration of hypoglycemia in type 1 diabetic patients, improves the quality of life of diabetic patients, and does not adversely affect key diabetes indicators such as TIR and GA
.
Yimaitong Endocrine Group Scan the QR code to join the "Yimaitong-Endocrine Group", you can enjoy the benefits of lecture review, Q&A and free guides~
