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    Home > Chemicals Industry > Chemical Technology > Issue 21/2021 - L-Homoserine achieves 50% efficient conversion

    Issue 21/2021 - L-Homoserine achieves 50% efficient conversion

    • Last Update: 2022-11-14
    • Source: Internet
    • Author: User
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    Recently, the research team of the Institute of Microbiology of the Chinese Academy of Sciences has made the fermentation level of L-homoserine exceed 84 g/L through systematic metabolic engineering transformation and fermentation process improvement, and the conversion rate has reached 50%, which has good economy

    Through the pathway coupling design, the research team established a fermentation path with an overall balance of reducing power, and reused the carbon dioxide released in the reducing force supply pathway, and the designed pathway realized the fermentation of glucose to L-homoserine without loss of carbon element
    This study lays a foundation for the industrial production of L-homoserine, and provides a new idea
    for improving the yield of other aspartic acid amino acids.

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