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Chinese scientists have synthesized 4 artificially designed Saccharomyces cerevisiae chromosomes using chemicals, marking another big step
towards "recreating life".
The results of the study were published in the internationally renowned academic journal Science on March 10, and China has become the second country
with eukaryotic genome design and construction capabilities after the United States.
Researchers from Tianjin University, Tsinghua University and Shenzhen BGI Institute of Genetics introduced that the study used small nucleotides to accurately synthesize living eukaryotic chromosomes, and for the first time achieved the complete matching of artificial genome synthesis sequence and design sequence, and the obtained yeast genome has complete life activity
.
In research, the exact match between the actual genome sequence and the design sequence is crucial
.
According to Dai Junbiao, a researcher at the School of Life Sciences at Tsinghua University, researchers have created rapid localization and precise repair methods for genomic defective targets to ensure that the chemically synthesized genome has high vitality
.