It is found that the intake index of calories is the leading cause of metabolic disorder

There is increasing evidence that proper calorie control can help prolong life span and delay the occurrence of age-related diseases Heat can limit the level of hormone and lipid metabolites, and change energy metabolism However, scientists do not know the amount of biochemical changes the body can withstand during heat control, nor can they be sure of their long-term effects Recently, Wang Yulan research group of Wuhan Institute of physical sciences and Liu Yong research group of Shanghai Institute of nutrition carried out an experiment for more than one year to study the effect of long-term diet intervention on metabolic disorder, and found that high calorie diet can affect the metabolism of lipid substances in the host Further research shows that the intake index of calories rather than the way of diet is the leading cause of metabolic disorder The researchers set up four groups of mice models: long-term low-fat diet group, low-fat calorie control group, high-fat calorie control group and high-fat diet group The metabonomics changes of host serum and urine samples under long-term dietary intervention were observed by using the technology of metabonomics detection based on NMR (http://www.chemdrug.com/sell/76/) It was found that high calorie diet disturbed lipid metabolism, glucose metabolism and nucleotide metabolism, and also disturbed the interaction between intestinal microflora and the body itself Most importantly, the study found that these metabolic changes are closely related to the caloric intake index, rather than the way of eating This also means that whether it is a high-fat or low-fat diet, as long as the proper control of calorie intake According to the introduction, the results of this study provide important guidance information for long-term dietary intervention The researchers believe that it is not necessary to talk about high oil and high fat food, and suggest that everyone develop a diet habit of low calorie intake as much as possible while ensuring the nutritional needs of the body.