It is found that the microbial composition and balance in the gut will change significantly after severe trauma

Intestinal tract plays an important role in injury response, and intestinal microbiome has many effects on human health (http:// However, it has not been clear how the intestinal flora of severely injured people will change Recently, a new study published in the journal trauma surgery & acute care open shows that the microbial composition and balance of intestine will change significantly within 72 hours after severe trauma These changes may affect the recovery or death of patients, and also help doctors delay the occurrence of serious symptoms In this study, the researchers examined (http:// the resolution samples of 12 patients with severe trauma, and analyzed (http:// the type and quantity of bacteria in them The samples were collected between 23 and 72 hours after the trauma The authors compared it with the resolution samples of 10 patients who had not been traumatized There was only one female with an average age of 29, but the age span was between 20 and 89 The first batch of samples showed that the intestinal microbial composition of the two groups was similar, but there was a significant difference from the second batch of samples 72 hours later, the results showed that "the number of Bacteroides, Clostridium and other bacteria in the intestine of trauma patients decreased sharply, while the number of Clostridium and Enterobacteriaceae increased significantly The researchers say this rapid mutation in gut microbiome has never been detected before, which may have potential implications for clinical diagnosis and treatment of severe trauma