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    Home > Active Ingredient News > Endocrine System > J Am Heart Assoc: Correlation analysis of cognitive impairment and cardiovascular events in diabetic patients

    J Am Heart Assoc: Correlation analysis of cognitive impairment and cardiovascular events in diabetic patients

    • Last Update: 2022-05-13
    • Source: Internet
    • Author: User
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    Adults with type 2 diabetes and cognitive impairment are more likely to experience major adverse cardiovascular events, stroke than adults without cognitive impairment, according to a study published today in the journal J Clin Endocrinol Metab or cardiovascular (CV) death
    .

    Low cognitive scores are a potential risk factor for cardiovascular disease (CVD).
    To assess the association of cognitive index scores with CVD prognosis, we collected data from 8772 patients with type 2 diabetes in the REWIND study, who were assessed at baseline, 2 Completion of Montreal Cognitive Assessment (MoCA) and Digital Sign Switching Test (DSST) at year, 5, and last follow-up

    .
    Each test was standardized according to the participant's country, and based on the geometric mean, those who scored 1.
    5 standard deviations below the national average on both tests were defined as having substantial cognitive impairment

    .
    The primary outcomes were CVD events, stroke events, and CV mortality

    .

    In the study cohort, 10.
    3% had substantial cognitive impairment, and the incidence of substantial cognitive impairment based on the geometric mean was 6%

    .
    Participants with substantial cognitive impairment had no significantly increased risk of major adverse CVD events after adjusting for proteinuria, predicted glomerular filtration rate, and retinopathy

    .
    However, in the fully adjusted model, patients with substantial cognitive impairment based on geometric means had a significantly higher risk of major adverse CVD events than those without cognitive impairment (aHR 1.
    38, 95% CI 1.
    09-1.
    77; P =0.
    009)

    .
    Substantial cognitive impairment (aHR 1.
    35, 95%CI 1.
    11-1.
    64; P=0.
    002) and substantial cognitive impairment based on geometric mean (aHR 1.
    54, 95%CI 1.
    22-1.
    93; P<0.
    001) versus no cognition increased risk of stroke or CV death compared with adults with disabilities

    .

    Original source:

    Original source:

    Minhas AS, Hong X, Wang G, et al.
    Mediterranean-Style Diet and Risk of Preeclampsia by Race in the Boston Birth Cohort .
    J Am Heart Assoc.
    2022 Apr 20: e022589.
    doi: 10.
    1161/JAHA.
    121.
    022589.
    Epub ahead of print.
    PMID: 35441523.

    Minhas AS, Hong X, Wang G, et al.
    Mediterranean-Style Diet and Risk of Preeclampsia by Race in the Boston Birth Cohort .
    J Am Heart Assoc.
    2022 Apr 20: e022589.
    doi: 10.
    1161/JAHA.
    121.
    022589.
    Epub ahead of print.
    PMID: 35441523.
    Mediterranean-Style Diet and Risk of Preeclampsia by Race in the Boston Birth Cohort

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