J Clin Anesth: The effect of intravenous lidocaine on the quality of recovery and analgesia after thoracoscopic surgery: a randomized controlled trial

Research purposes

Intraoperative intravenous lidocaine as an auxiliary drug for general anesthesia has been widely accepted, which can reduce the use of opioids and promote recovery; we hypothesize that perioperative intravenous infusion of lidocaine in thoracoscopic surgery (VATS) patients can improve the operation Pain afterwards and improve the quality of recovery (QOR).

design

Prospective, single-center, double-blind, randomized, placebo-controlled clinical trial.

Range setting

Single institution, top three affiliated hospitals of medical universities.

Subject

Adult patients aged 18-65 who receive VATS are eligible to participate.

Intervention

The patients enrolled in this study were randomly divided into two groups; one group received intravenous lidocaine (an intravenous bolus of 1.

Observation index

The main observation index is the QOR-15 score after 24 hours of observation; the secondary indexes include postoperative pain score, total opioid use, recovery time, PACU stay time, incidence of adverse events, and patient satisfaction.

Main result

There was no statistically significant difference in QOR-15 scores between lidocaine group and normal saline group at 24 hours after surgery (lidocaine group: median 117, interquartile range (IQR) 113.

in conclusion

The current research results do not support the use of perioperative intravenous lidocaine as a potential strategy for improving postoperative pain and QOR in VATS patients.

Original source:

Yusheng Yao, et al.