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Although the prognosis of patients with primary thin skin melanoma (T1, ≤1.
This study contains two cohorts, the development cohort (n=25930, Dutch population) and the validation cohort (n=2968, Australian melanoma patients).
The median follow-up time of patients in the development cohort was 6.
The median follow-up time for the development cohort was 6.
10-year calibration chart and receiver operating characteristic curve of local, regional and distant recurrence-free survival (RFS)
10-year calibration chart and receiver operating characteristic curve of local, regional and distant recurrence-free survival (RFS)In the development model, the C-statistics of local RFS, regional RFS and distant RFS are 0.
Using the nomogram, the C-statistics of the development cohort increased by 9%-12%, and the C-statistics of the validation cohort increased by 11%-15% compared with the model that only included T stage and sentinel lymph node status.
The nomogram developed in this research can accurately identify patients with thin melanoma at high risk of recurrence, and help formulate reasonable treatment strategies, thereby improving the prognosis of patients.
Original source:
El Sharouni Mary-Ann, Ahmed Tasnia, Varey Alexander HR et al.
org/10.
1200/JCO.
20.
02446">Development and Validation of Nomograms to Predict Local , Regional, and Distant Recurrence in Patients With Thin (T1) Melanomas in this message
