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Chronic pancreatitis (CP) is an inflammatory disease of pancreatic fibrosis.
interventions are critical to improving long-term outcomes before CP is established and irreversible.
2009, Japan proposed the world's first early CP diagnostic standards, but its clinical practicality is still difficult to determine.
a multi-center, forward-looking study aimed at clarifying whether early CP patients will progress to a clear CP, the results of which were published online in J Gastroenterol.
follow-up patients diagnosed with early CP for 2 years based on Japanese diagnostic criteria.
analysis of patients' clinical data, including symptoms, alcohol and smoking status, laboratory data, imaging results, and treatment methods.
results showed that out of 83 patients who completed two years of follow-up, 4 (4.8%) developed CP.
48 (57.8%) patients had no change in diagnosis and 31 (37.3%) had a downgrade.
four patients were male, drinkers and smokers (3 now, 1 was former) and continued to drink.
clinical data from the comparative progression group (n-4) and non-progressive group (n-79) found that the ecaused (alcohol-related), smoking status and the availability of acute pancreatitis attacks were associated with a clear progression of CP.
, the results show that Japan's diagnostic criteria can be identified before certain patients develop clear CPs, while most patients do not progress.
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