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    Home > Active Ingredient News > Infection > J Gastroenterology: Serum soluble programmed death 1 (sPD-1) predicts the extent of spontaneous HBeAg seroclearance in chronic hepatitis B

    J Gastroenterology: Serum soluble programmed death 1 (sPD-1) predicts the extent of spontaneous HBeAg seroclearance in chronic hepatitis B

    • Last Update: 2022-05-26
    • Source: Internet
    • Author: User
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    Hepatitis B virus e-antigen (HBeAg) seropositivity is associated with active hepatitis B virus (HBV) replication, highly virulent transmission, and an increased risk of inflammation


    Hepatitis B virus e-antigen (HBeAg) seropositivity is associated with active hepatitis B virus (HBV) replication, highly virulent transmission, and an increased risk of inflammation


     

     

    We tested baseline serum samples of 488 HBeAg seropositive patients in the REVEAL-HBV cohort for sPD-1 levels


     

    Results of the study found lower baseline sPD-1 levels [aRR (95% CI): 2.


     

    The results of this study demonstrate that serum sPD-1 levels can be used as a novel immunological predictor of spontaneous HBeAg seroclearance in patients with chronic hepatitis


    The results of this study demonstrate that serum sPD-1 levels can be used as a novel immunological predictor of spontaneous HBeAg seroclearance in patients with chronic hepatitis


    Yu-Ju Chu.




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