J Gastroenterology: Zinc deficiency is a predictor of efficacy in chronic liver disease treatment

Chronic liver disease is likely to present symptoms of zinc deficiency
.

Several factors, such as insufficient dietary intake, impaired intestinal absorption, and excessive urination, may be responsible for lower systemic zinc levels

Chronic liver disease is likely to present symptoms of zinc deficiency

 

The study was an observational single-center design
.

The researchers performed a statistical analysis between zinc levels and treatment effect by retrospectively analyzing the medical records of 666 patients with chronic liver disease who had measured serum zinc levels

 

The results of the study showed that the alcoholic liver disease (ALD) group had significantly lower serum zinc levels than other groups (hepatitis C virus [HCV] group and hepatitis B virus [HBV] group) (P < 0.
01)
.

Nutritional prognosis index (CONUT) and albumin-bilirubin grade (ALBI) score (r = 0.

 

The results of this study confirmed that ALD, CONUT score, aspartate aminotransferase and hemoglobin were risk factors for zinc deficiency in chronic liver disease
.

Zinc deficiency rates are high, especially in ALD, even in patients classified as mALBI grade 1

The results of this study confirmed that ALD, CONUT score, aspartate aminotransferase and hemoglobin were risk factors for zinc deficiency in chronic liver disease

Soichi Iritani.

The useful predictors of zinc deficiency for the management of chronic liver disease.
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