J Gerontol A Biol Sci Med Sci: Fructosamine can predict the risk of death in people over 80 years old

The level of glycosylated hemoglobin (HbA1c) has been widely used to monitor long-term blood sugar control

Some guidelines suggest that in the elderly with limited life expectancy or multiple chronic diseases, alternative blood glucose markers of glycosylated hemoglobin can be selected to monitor blood glucose control

This study evaluated the correlation of fructosamine, albumin-corrected fructosamine (AlbF) and fasting blood glucose (FPG) with mortality in diabetic and non-diabetic populations to determine which markers are more predictive of subjects 80 years and older Death rate

A total of 2238 subjects from the healthy aging and biomarker cohort study (2012-2018) were included, of which 207 subjects had diabetes at baseline

Correlation between fructosamine levels and all-cause mortality, CVD mortality, and non-CVD mortality in non-diabetic subjects

In total, 1191 deaths were recorded during the 6793 person-year follow-up period

The correlation between FPG and non-diabetic subjects' all-cause mortality, CVD mortality, and non-CVD mortality

All in all, the higher the fructosamine, AlbF, and fasting blood glucose levels, the higher the risk of all-cause death and non-cardiovascular death in the elderly, among which fructosamine has the highest predictive value

Zhou Jinhui,Lv Yuebin,Zhao Feng et al.