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Background and goals: According to the relevant research, the prevalence of non-alcoholic fatty liver disease (NAFLD) is on the rise among young people and has potential adverse effects on women of childbearing age.
whether NAFLD during pregnancy creates a greater risk to the health of mothers or perinatal women.
, the researchers conducted a study on the subject.
method researchers used discharge data from a sample of hospitalized patients in the United States to assess the incidence of NAFLD in pregnant women after 20 weeks of pregnancy and compared it with the outcomes of other pregnant women with chronic liver disease (CLD) or non-CLD.
results include prematal birth, postpartum bleeding, complications of hypertension (pre-eclampsia, eclampsia and/or hemolysis, elevated liver enzymes and hyplate syndrome), and maternal or fetal mortality, and time trends through linear regression testing.
results were corrected for age, race, multiple pregnancy and pre-pregnancy diabetes, obesity, blood lipid abnormalities, and hypertension.
18574225 pregnancy records, 5,640 had NAFLD, while 115,210 had other non-NAFLD CLDs.
NAFLD pregnancy from 10.5 in 2007 / every 100,000 pregnancies to 2015 (28.9 / 100,000 (p .lt;0.0) 01) Increased nearly twice as many patients with NAFLD during pregnancy (8% VS 23%), complications of hypertension (4% VS 16%), postpartum haemorrhage (5% VS 6%) than other groups.
and premature birth (5% VS 9%), all p-values are 0.01.
, NAFLD was associated with complications of hypertension, premature birth, and postpartum haemorrhage death compared to no CLD.
concluded that the prevalence of NAFLD during pregnancy has nearly tripled in the past decade and has been associated with complications of high blood pressure, postpartum bleeding and premature birth.
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