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J Infect Dis: New coronavirus-specific T cells still have high expression 12 months after infection

 Last Update: 2021-11-02
 Source: Internet
 Author: User

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therapeutic antibodies

caco 2 cells

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The new coronary pneumonia caused by the new coronavirus is a viral infection.
Cellular immunity plays an important role in resisting the progression of the disease.
Therefore, identifying and amplifying the specific cellular immune response to SARS-CoV-2 is to enhance and improve patients with new coronavirus The key to clinical results
.

Previous studies have shown that after 10 months of infection with the new coronavirus, SARS-CoV-2 specific T cells still exist in the peripheral blood

The new coronary pneumonia caused by the new coronavirus is a viral infection.

The researchers collected patients in a prospective cohort study within 12 months after SARS-CoV-2 infection.
These patients represented a range of different phenotypes of disease severity
.

Then use intracellular cytokine staining and spectral flow cytometry to study the function, phenotype and proportion of SARS-CoV-2 specific T cells

The results of the study showed that SARS-CoV-2 specific antibodies and specific T cells were still detected 12 months after infection
.

The severity of the acute disease is related to the higher frequency of SARS-CoV-2 specific CD4T-positive cells and antibodies at 12 months

This study confirmed that SARS-CoV-2 infection can still induce detectable multifunctional memory T cells 12 months after infection.
This phenomenon occurs more frequently in people who initially suffer from serious diseases
.

Original source:

Zhongyan Lu.

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