J INTERN MED: Non-alcoholic fatty liver disease associated with reduced mechanical energy efficiency of myocardial muscle

!---- Non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular disease (CVD), although its underlying mechanism is not yet fully understoodhas been shown to show that reduced cardiomyocardial energy efficiency (MEE) is an independent predictor of CVDrecently published a study in Journal of Internal Medicine, an authoritative journal in the field of internal medicine, to assess the link between NAFLD and damaged MEEsthe use of an echocardiogram to determine the presence or absence of NAFLD divided 699 non-diabetic patients into two groups and evaluated myocardial MEE using an effective echocardiogramPatients withNAFLD had higher systolic pressure (SBP) and diastolic pressure (DBP), triglycerides, fasting and post-meal blood sugar, hypersensitivity C-reactive protein (hsCRP), and the insulin resistance (IR) index and HDL values estimated by HOMA-IR and liver IR were lower than those without NAFLDNAFLD is associated with increased oxygen demand levels in myocardial muscle and lower MEE valuesMEE was negatively correlated with men, age, BMI, waist circumference, SBP, DBP, total cholesterol, triglycerides, fasting and post-meal blood sugar, HOMA-IR and liver IR indices, hsCRP, and positively correlated with HDL levelsin multivariate regression analysis, NAFLD is related to MEE (beta-0.09, P-0.04), regardless of age, sex, waist circumference, SBP, DBP, total cholesterol and HDL cholesterol, triglycerides, glucose tolerance, and hsCRPit can be seen that ultrasound determined nAFLD is associated with the reduction of MEE, which is a predictor of adverse cardiovascular eventsrelationship between NAFLD and damaged MEE depends on IR