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    Home > Active Ingredient News > Endocrine System > J INTERN MED: Patients with hip fractures are at increased risk of fracture after stopping anti-osteoporosis drugs

    J INTERN MED: Patients with hip fractures are at increased risk of fracture after stopping anti-osteoporosis drugs

    • Last Update: 2021-07-31
    • Source: Internet
    • Author: User
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    Recently, an authoritative journal in the field of internal medicine published a research article in the Journal of Internal Medicine.


    Osteoporosis

    The researchers conducted a comparative study of the effectiveness of a cohort study design based on a national population


    According to the patient's subsequent medication mode, patients are divided into continuous or non-continuous denosumab or bisphosphonate users


    Compared with those who continued to use denosumab, non-sustained denosumab users had severe osteoporotic fractures (hazard ratio (HR)=1.


    It can be seen that discontinuation of denosumab will lead to an increased risk of osteoporotic fractures, especially vertebral fractures, and the increased risk often manifests within one year after stopping the drug


    Discontinuation of denosumab will lead to an increased risk of osteoporotic fractures, especially vertebral fractures, and the increased risk often manifests within one year after stopping the drug


    Original source:

    Shau-Huai Fu.


    Increased fracture risk after discontinuation of anti- osteoporosis medications among hip fracture patients: a population-based cohort study

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